Cellosaurus cell line WM3060 (CVCL

Cellosaurus WM3060 (CVCL_6796)

[Text version]

Cell line name

WM3060

Synonyms

WM-3060; WM 3060; WC00126

Accession

CVCL_6796

Resource Identification Initiative

To cite this cell line use: WM3060 (RRID:CVCL_6796)

Comments

Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Misspelling: VM3060; Cosmic=2230118.
Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; None_reported; -; Zygosity=- (Wistar).
Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=25056119; Wistar).
Mutation; HGNC; HGNC:9801; RAC1; Simple; p.Pro29Ser (c.85C>T); ClinVar=VCV000376362; Zygosity=Heterozygous (PubMed=25056119).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_AP76 ! WM1960
CVCL_AP77 ! WM2013

Sex of cell

Male

Age at sampling

55Y

Category

Cancer cell line

STR profile

Source(s): Wistar

Markers:

Amelogenin	X,Y
CSF1PO	10
D2S1338	18,21
D3S1358	14,18
D5S818	11
D7S820	10,12
D8S1179	10,16
D13S317	11
D16S539	8,12
D18S51	19
D19S433	13,14
D21S11	29
FGA	22
TH01	6,8
TPOX	8
vWA	18

Web pages

https://www.wistar.org/our-scientists/meenhard-herlyn

Publications

PubMed=25056119; DOI=10.1158/0008-5472.CAN-14-1232-T; PMCID=PMC4167745
Watson I.R., Li L.-R., Cabeceiras P.K., Mahdavi M., Gutschner T., Genovese G., Wang G.-C., Fang Z.-N., Tepper J.M., Stemke-Hale K., Tsai K.Y., Davies M.A., Mills G.B., Chin L.
The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF.
Cancer Res. 74:4845-4852(2014)

Cross-references

Cell line collections (Providers)

Coriell; WC00126 - Discontinued
Rockland; WM3060-01-0001

Cell line databases/resources

cancercelllines; CVCL_6796

Encyclopedic resources

Wikidata; Q54994227

Gene expression databases

GEO; GSM186481
GEO; GSM186482

Polymorphism and mutation databases

Cosmic; 2159440
Cosmic; 2230118
Progenetix; CVCL_6796

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number