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Cellosaurus WM3060 (CVCL_6796)

[Text version]
Cell line name WM3060
Synonyms WM-3060; WM 3060; WC00126
Accession CVCL_6796
Resource Identification Initiative To cite this cell line use: WM3060 (RRID:CVCL_6796)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Misspelling: VM3060; Cosmic=2230118.
Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; None_reported; -; Zygosity=- (Wistar).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=25056119; Wistar).
  • Mutation; HGNC; 9801; RAC1; Simple; p.Pro29Ser (c.85C>T); ClinVar=VCV000376362; Zygosity=Heterozygous (PubMed=25056119).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_AP76 ! WM1960
CVCL_AP77 ! WM2013
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX,Y
CSF1PO10
D2S133818,21
D3S135814,18
D5S81811
D7S82010,12
D8S117910,16
D13S31711
D16S5398,12
D18S5119
D19S43313,14
D21S1129
FGA22
TH016,8
TPOX8
vWA18

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=25056119; DOI=10.1158/0008-5472.CAN-14-1232-T
Watson I.R., Li L.-R., Cabeceiras P.K., Mahdavi M., Gutschner T., Genovese G., Wang G.-C., Fang Z.-N., Tepper J.M., Stemke-Hale K., Tsai K.Y., Davies M.A., Mills G.B., Chin L.
The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF.
Cancer Res. 74:4845-4852(2014)

Cross-references
Cell line collections (Providers) Coriell; WC00126 - Discontinued
Rockland; WM3060-01-0001
Cell line databases/resources cancercelllines; CVCL_6796
Encyclopedic resources Wikidata; Q54994227
Gene expression databases GEO; GSM186481
GEO; GSM186482
Polymorphism and mutation databases Cosmic; 2159440
Cosmic; 2230118
Progenetix; CVCL_6796
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number24