ID   WM3060
AC   CVCL_6796
SY   WM-3060; WM 3060; WC00126
DR   cancercelllines; CVCL_6796
DR   Coriell; WC00126
DR   Cosmic; 2159440
DR   Cosmic; 2230118
DR   GEO; GSM186481
DR   GEO; GSM186482
DR   Progenetix; CVCL_6796
DR   Rockland; WM3060-01-0001
DR   Wikidata; Q54994227
RX   PubMed=25056119;
WW   https://www.wistar.org/our-scientists/meenhard-herlyn
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; None_reported; -; Zygosity=- (Wistar).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=25056119; Wistar).
CC   Sequence variation: Mutation; HGNC; 9801; RAC1; Simple; p.Pro29Ser (c.85C>T); ClinVar=VCV000376362; Zygosity=Heterozygous (PubMed=25056119).
CC   Omics: Transcriptome analysis by microarray.
CC   Misspelling: VM3060; Cosmic=2230118.
CC   Discontinued: Coriell; WC00126; probable.
CC   Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.
ST   Source(s): Wistar
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 8,12
ST   D18S51: 19
ST   D19S433: 13,14
ST   D21S11: 29
ST   D2S1338: 18,21
ST   D3S1358: 14,18
ST   D5S818: 11
ST   D7S820: 10,12
ST   D8S1179: 10,16
ST   FGA: 22
ST   TH01: 6,8
ST   TPOX: 8
ST   vWA: 18
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_AP76 ! WM1960
OI   CVCL_AP77 ! WM2013
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 24
//
RX   PubMed=25056119; DOI=10.1158/0008-5472.CAN-14-1232-T;
RA   Watson I.R., Li L.-R., Cabeceiras P.K., Mahdavi M., Gutschner T.,
RA   Genovese G., Wang G.-C., Fang Z.-N., Tepper J.M., Stemke-Hale K., Tsai K.Y.,
RA   Davies M.A., Mills G.B., Chin L.;
RT   "The RAC1 P29S hotspot mutation in melanoma confers resistance to
RT   pharmacological inhibition of RAF.";
RL   Cancer Res. 74:4845-4852(2014).
//