Cellosaurus logo
expasy logo

Cellosaurus HTOG (CVCL_6656)

[Text version]
Cell line name HTOG
Accession CVCL_6656
Resource Identification Initiative To cite this cell line use: HTOG (RRID:CVCL_6656)
Comments Population: Japanese.
Characteristics: Established from the granulosa cells of a granulosa-theca cell tumor.
Doubling time: 46.2 hours (Note=At 5th passage), 28.4 hours (Note=At 20th passage), 23.8 hours (Note=At 40th passage) (PubMed=6323807); 25 hours (PubMed=10457904).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Disease Ovarian granulosa cell tumor (NCIt: C6261)
Maligant granulosa cell tumor of the ovary (ORDO: Orphanet_99915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6657 ! HTOT
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
Publications

PubMed=6323807; DOI=10.1093/jnci/72.4.789
Ishiwata I., Ishiwata C., Soma M., Kobayashi N., Ishikawa H.
Establishment and characterization of an estrogen-producing human ovarian granulosa tumor cell line.
J. Natl. Cancer Inst. 72:789-800(1984)

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Ishiwata I., Ishiwata C., Nozawa S., Ishikawa H.
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Ishiwata I., Ishiwata C., Soma M., Ono I., Nakaguchi T., Ishikawa H.
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

PubMed=9436037
Soma M., Ishiwata I., Ishiwata C., Nakaguchi T., Ono I., Kiguchi K., Hashimoto H., Tachibana T., Ishikawa H., Nozawa S.
Tissue reconstruction of gynecologic tumor cells in the rotation culture system.
Hum. Cell 10:175-181(1997)

PubMed=10457904
Ishiwata I., Sudo T., Kiguchi K., Ishikawa H.
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Havelock J.C., Rainey W.E., Carr B.R.
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

Cross-references
Encyclopedic resources Wikidata; Q54896671
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17