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Cellosaurus BHP 18-21 (CVCL_6282)

[Text version]
Cell line name BHP 18-21
Synonyms BHP18-21; BHP-18; BHP18
Accession CVCL_6282
Resource Identification Initiative To cite this cell line use: BHP 18-21 (RRID:CVCL_6282)
Comments Problematic cell line: Contaminated. Shown to be a mixture of M14 and TPC-1 cell lines (DOI=10.1016/j.yamp.2018.07.005). Originally thought to originate from a thyroid gland papillary carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00571.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1395 (M14)
Parent: CVCL_6298 (TPC-1)
Category Hybrid cell line
STR profile Source(s): DOI=10.1016/j.yamp.2018.07.005

Markers:
AmelogeninX
D3S135814,16,17
D5S8188,10,11,13
D7S8208,10,11
D8S117911,13,17
D13S31711,12
D18S5113,16,17
D21S1130,31.2
FGA20,21
vWA14,16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=8675585; DOI=10.1210/jcem.81.7.8675585
Ohta K., Pang X.-P., Berg L., Hershman J.M.
Antitumor actions of cytokines on new human papillary thyroid carcinoma cell lines.
J. Clin. Endocrinol. Metab. 81:2607-2612(1996)

PubMed=9253346; DOI=10.1210/jcem.82.8.4136
Ohta K., Pang X.-P., Berg L., Hershman J.M.
Growth inhibition of new human thyroid carcinoma cell lines by activation of adenylate cyclase through the beta-adrenergic receptor.
J. Clin. Endocrinol. Metab. 82:2633-2638(1997)

DOI=10.1016/j.yamp.2018.07.005
Nims R.W.
Historical and current methods for detecting interspecies and intraspecies cell mixtures and thereby assuring cell line purity.
Adv. Mol. Pathol. 1:253-264(2018)

Cross-references
Encyclopedic resources Wikidata; Q54796497
Polymorphism and mutation databases Cosmic; 1005452
Cosmic; 1094770
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number11