ID   BHP 18-21
AC   CVCL_6282
SY   BHP18-21; BHP-18; BHP18
DR   Cosmic; 1005452
DR   Cosmic; 1094770
DR   Wikidata; Q54796497
RX   DOI=10.1016/j.yamp.2018.07.005;
RX   PubMed=8675585;
RX   PubMed=9253346;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a mixture of M14 and TPC-1 cell lines (DOI=10.1016/j.yamp.2018.07.005). Originally thought to originate from a thyroid gland papillary carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00571.
ST   Source(s): DOI=10.1016/j.yamp.2018.07.005
ST   Amelogenin: X
ST   D13S317: 11,12
ST   D18S51: 13,16,17
ST   D21S11: 30,31.2
ST   D3S1358: 14,16,17
ST   D5S818: 8,10,11,13
ST   D7S820: 8,10,11
ST   D8S1179: 11,13,17
ST   FGA: 20,21
ST   vWA: 14,16,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1395 ! M14
HI   CVCL_6298 ! TPC-1
CA   Hybrid cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 11
//
RX   DOI=10.1016/j.yamp.2018.07.005;
RA   Nims R.W.;
RT   "Historical and current methods for detecting interspecies and
RT   intraspecies cell mixtures and thereby assuring cell line purity.";
RL   Adv. Mol. Pathol. 1:253-264(2018).
//
RX   PubMed=8675585; DOI=10.1210/jcem.81.7.8675585;
RA   Ohta K., Pang X.-P., Berg L., Hershman J.M.;
RT   "Antitumor actions of cytokines on new human papillary thyroid
RT   carcinoma cell lines.";
RL   J. Clin. Endocrinol. Metab. 81:2607-2612(1996).
//
RX   PubMed=9253346; DOI=10.1210/jcem.82.8.4136;
RA   Ohta K., Pang X.-P., Berg L., Hershman J.M.;
RT   "Growth inhibition of new human thyroid carcinoma cell lines by
RT   activation of adenylate cyclase through the beta-adrenergic
RT   receptor.";
RL   J. Clin. Endocrinol. Metab. 82:2633-2638(1997).
//