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Cellosaurus EL-4-B5 (CVCL_5I39)

[Text version]
Cell line name EL-4-B5
Synonyms EL-4 B5; EL4-B5; EL4B5
Accession CVCL_5I39
Resource Identification Initiative To cite this cell line use: EL-4-B5 (RRID:CVCL_5I39)
Comments Characteristics: Can be used as a feeder layer to generate B cell cultures yielding human monoclonal antibodies (Kerafast=EVU301).
Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse precursor T cell lymphoblastic lymphoma/leukemia (NCIt: C21925)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N.
Hierarchy Parent: CVCL_5680 (EL4.BU.1.OUAr.1.1)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7691726
Kwekkeboom J., de Boer M., Tager J.M., de Groot C.
CD40 plays an essential role in the activation of human B cells by murine EL4B5 cells.
Immunology 79:439-444(1993)

Cross-references
Cell line collections (Providers) Kerafast; EVU301
Encyclopedic resources Wikidata; Q54832205
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number10