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Cellosaurus WSU-HN8 (CVCL_5517)

[Text version]
Cell line name WSU-HN8
Synonyms HN8; Wayne State University-Head and Neck 8
Accession CVCL_5517
Resource Identification Initiative To cite this cell line use: WSU-HN8 (RRID:CVCL_5517)
Comments Part of: OPC-22 oral and pharyngeal cancer cell line panel.
Omics: Deep exome analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5522 ! WSU-HN22
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=25275298

Markers:
AmelogeninX,Y
CSF1PO12,13
D3S135817
D5S81811,12
D7S8208
D8S117911,12
D13S31713
D16S5399,12
D18S5113,19
D21S1130
FGA22
Penta D15
Penta E5,13
TH016,9
TPOX8
vWA17,18

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Publications

PubMed=8001221; DOI=10.1093/carcin/15.12.2683
Yeudall W.A., Crawford R.Y., Ensley J.F., Robbins K.C.
MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma.
Carcinogenesis 15:2683-2686(1994)

PubMed=7705939; DOI=10.1002/ijc.2910610117
Cardinali M., Pietraszkiewicz H., Ensley J.F., Robbins K.C.
Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies.
Int. J. Cancer 61:98-103(1995)

PubMed=9389571; DOI=10.1002/(SICI)1097-0215(19971114)73:4<551::AID-IJC16>3.0.CO;2-C
Patel V., Jakus J., Harris C.M., Ensley J.F., Robbins K.C., Yeudall W.A.
Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck.
Int. J. Cancer 73:551-555(1997)

PubMed=25275298; DOI=10.18632/oncotarget.2417; PMCID=PMC4253406
Martin D., Abba M.C., Molinolo A.A., Vitale-Cross L., Wang Z.-Y., Zaida M., Delic N.C., Samuels Y., Lyons J.G., Gutkind J.S.
The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies.
Oncotarget 5:8906-8923(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5517
Encyclopedic resources Wikidata; Q54994491
Polymorphism and mutation databases Cosmic; 922080
Cosmic; 2296296
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18