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Cellosaurus BEL-7402/5-FU (CVCL_5493)

[Text version]
Cell line name BEL-7402/5-FU
Synonyms Bel7402/5-FU; BEL-7402/FU; Bel/5Fu
Accession CVCL_5493
Resource Identification Initiative To cite this cell line use: BEL-7402/5-FU (RRID:CVCL_5493)
Comments Problematic cell line: Contaminated. Parent cell line (BEL-7402) has been shown to be a HeLa derivative.
Population: African American.
Doubling time: 42.3 +- 3.3 hours (PubMed=23167424).
Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Deep quantitative proteome analysis.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5492 (BEL-7402)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=16696913; DOI=10.3736/jcim20060309
Gu W., Zhang Y.-N., Li B., Han J., Cheng B.-B., Ling C.-Q.
Establishment of a multidrug-resistant cell line BEL-7402/5-FU of human hepatocellular carcinoma and its biological characteristics.
Zhong Xi Yi Jie He Xue Bao 4:265-270(2006)

PubMed=23167424; DOI=10.7314/APJCP.2012.13.9.4807
Gu W., Fang F.-F., Li B., Cheng B.-B., Ling C.-Q.
Characterization and resistance mechanisms of a 5-fluorouracil-resistant hepatocellular carcinoma cell line.
Asian Pac. J. Cancer Prev. 13:4807-4814(2012)

Chemistry resources ChEMBL-Cells; CHEMBL4482981
ChEMBL-Targets; CHEMBL4483230
PubChem_Cell_line; CVCL_5493
Encyclopedic resources Wikidata; Q54795970
Proteomic databases PRIDE; PXD015917
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19