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Cellosaurus KOC-7C (CVCL_5307)

[Text version]
Cell line name KOC-7C
Synonyms KOC-7c; KOC7C
Accession CVCL_5307
Resource Identification Initiative To cite this cell line use: KOC-7C (RRID:CVCL_5307)
Comments Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: 45.9 hours (CelloPub=CLPUB00067).
Omics: Deep exome analysis.
Omics: Deep quantitative phosphoproteome analysis.
Omics: Genome sequenced.
Omics: Protein expression by reverse-phase protein arrays.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
HLA typing Source: PubMed=9023415
Class I
HLA-AA*02:01,31:01
HLA-BB*51,52
Disease Ovarian clear cell adenocarcinoma (NCIt: C40078)
Clear cell adenocarcinoma of the ovary (ORDO: Orphanet_398971)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): PubMed=30485824

Markers:
AmelogeninX
CSF1PO11,12
D5S81811
D7S8208,11,12
D13S31711,12
D16S5399,12
D21S1131,32
TH017,9
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

CLPUB00067
Tomioka Y.
Establishment and characterization of three human ovarian clear cell carcinoma cell lines (KOC-4c, KOC-5c, KOC-7c).
J. Kurume Med. Assoc. 61:323-333(1998)

PubMed=15534119; DOI=10.1158/1078-0432.CCR-04-0279
Takemoto Y., Yano H., Momosaki S., Ogasawara S., Nishida N., Kojiro S., Kamura T., Kojiro M.
Antiproliferative effects of interferon-alphaCon1 on ovarian clear cell adenocarcinoma in vitro and in vivo.
Clin. Cancer Res. 10:7418-7426(2004)

PubMed=26388441; DOI=10.1016/j.cell.2015.08.056
Creixell P., Schoof E.M., Simpson C.D., Longden J., Miller C.J., Lou H.J., Perryman L., Cox T.R., Zivanovic N., Palmeri A., Wesolowska-Andersen A., Helmer-Citterich M., Ferkinghoff-Borg J., Itamochi H., Bodenmiller B., Erler J.T., Turk B.E., Linding R.
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.
Cell 163:202-217(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096
Papp E., Hallberg D., Konecny G.E., Bruhm D.C., Adleff V., Noe M., Kagiampakis I., Palsgrove D., Conklin D., Kinose Y., White J.R., Press M.F., Drapkin R.I., Easwaran H., Baylin S.B., Slamon D.J., Velculescu V.E., Scharpf R.B.
Integrated genomic, epigenomic, and expression analyses of ovarian cancer cell lines.
Cell Rep. 25:2617-2633(2018)

Cross-references
Anatomy/cell type resources BTO; BTO:0004970
Biological sample resources BioSample; SAMN02800474
Encyclopedic resources Wikidata; Q54900277
Gene expression databases GEO; GSM659380
Polymorphism and mutation databases Cosmic; 2074243
Cosmic; 2482706
Proteomic databases PRIDE; PXD000901
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number18