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Cellosaurus Y-MESO-21 (CVCL_5180)

[Text version]
Cell line name Y-MESO-21
Accession CVCL_5180
Resource Identification Initiative To cite this cell line use: Y-MESO-21 (RRID:CVCL_5180)
Comments Population: Japanese.
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Sequence variations
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 66Y
Category Cancer cell line
Publications

PubMed=19380521; DOI=10.1093/carcin/bgp097
Kawaguchi K., Murakami H., Taniguchi T., Fujii M., Kawata S., Fukui T., Kondo Y., Osada H., Usami N., Yokoi K., Ueda Y., Yatabe Y., Ito M., Horio Y., Hida T., Sekido Y.
Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells.
Carcinogenesis 30:1097-1105(2009)

PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164
Murakami H., Mizuno T., Taniguchi T., Fujii M., Ishiguro F., Fukui T., Akatsuka S., Horio Y., Hida T., Kondo Y., Toyokuni S., Osada H., Sekido Y.
LATS2 is a tumor suppressor gene of malignant mesothelioma.
Cancer Res. 71:873-883(2011)

PubMed=22286761; DOI=10.1038/onc.2012.5
Mizuno T., Murakami H., Fujii M., Ishiguro F., Tanaka I., Kondo Y., Akatsuka S., Toyokuni S., Yokoi K., Osada H., Sekido Y.
YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes.
Oncogene 31:5117-5122(2012)

PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387
Hakiri S., Osada H., Ishiguro F., Murakami H., Murakami-Tonami Y., Yokoi K., Sekido Y.
Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells.
Cancer Sci. 106:990-999(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5180
Encyclopedic resources Wikidata; Q54995140
Gene expression databases GEO; GSM552528
GEO; GSM850288
Polymorphism and mutation databases Cosmic; 2759221
Progenetix; CVCL_5180
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16