Cellosaurus cell line SNU-1460 (CVCL

Cellosaurus SNU-1460 (CVCL_5026)

[Text version]

Cell line name

SNU-1460

Synonyms

SNU1460

Accession

CVCL_5026

Resource Identification Initiative

To cite this cell line use: SNU-1460 (RRID:CVCL_5026)

Comments

Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 67 hours (PubMed=20176655); 48 hours (PubMed=31228769).
Microsatellite instability: Stable (MSS) (PubMed=20176655; PubMed=25926053).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

25Y

Category

Cancer cell line

STR profile

Source(s): KCLB=01460; PubMed=20176655; PubMed=25926053; PubMed=31228769; Technion Genomics Center

Markers:

Amelogenin	X
CSF1PO	12
D1S1656	16,17
D2S441	11
D2S1338	23,24
D3S1358	15,17
D5S818	11
D7S820	8,11
D8S1179	13
D10S1248	15
D12S391	17,19
D13S317	9,12
D16S539	10
D18S51	13
D19S433	13,14.2
D21S11	30.2,31
D22S1045	16
FGA	21,23
Penta D	10,11
Penta E	13
TH01	6,7
TPOX	8,11
vWA	14,18

Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=31228769; DOI=10.1016/j.tranon.2019.05.019; PMCID=PMC6600802
Kim S.-C., Shin R., Seo H.-Y., Kim M., Park J.W., Jeong S.-Y., Ku J.-L.
Identification of a novel fusion gene, FAM174A-WWC1, in early-onset colorectal cancer: establishment and characterization of four human cancer cell lines from early-onset colorectal cancers.
Transl. Oncol. 12:1185-1195(2019)

Cross-references

Cell line collections (Providers)

KCLB; 01460

Cell line databases/resources

cancercelllines; CVCL_5026
ColonAtlas; SNU1460

Encyclopedic resources

Wikidata; Q54955116

Gene expression databases

GEO; GSM1448158

Polymorphism and mutation databases

Cosmic; 1322291
IARC_TP53; 28478

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number