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Cellosaurus SNU-1460 (CVCL_5026)

[Text version]
Cell line name SNU-1460
Synonyms SNU1460
Accession CVCL_5026
Resource Identification Initiative To cite this cell line use: SNU-1460 (RRID:CVCL_5026)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 67 hours (PubMed=20176655); 48 hours (PubMed=31228769).
Microsatellite instability: Stable (MSS) (PubMed=20176655; PubMed=25926053).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 25Y
Category Cancer cell line
STR profile Source(s): Technion Genomics Center BCF; KCLB=01460; PubMed=20176655; PubMed=25926053; PubMed=31228769

Markers:
AmelogeninX
CSF1PO12
D1S165616,17
D2S44111
D2S133823,24
D3S135815,17
D5S81811
D7S8208,11
D8S117913
D10S124815
D12S39117,19
D13S3179,12
D16S53910
D18S5113
D19S43313,14.2
D21S1130.2,31
D22S104516
FGA21,23
Penta D10,11
Penta E13
TH016,7
TPOX8,11
vWA14,18

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Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=31228769; DOI=10.1016/j.tranon.2019.05.019
Kim S.-C., Shin R., Seo H.-Y., Kim M., Park J.W., Jeong S.-Y., Ku J.-L.
Identification of a novel fusion gene, FAM174A-WWC1, in early-onset colorectal cancer: establishment and characterization of four human cancer cell lines from early-onset colorectal cancers.
Transl. Oncol. 12:1185-1195(2019)

Cross-references
Cell line collections (Providers) KCLB; 01460
Cell line databases/resources cancercelllines; CVCL_5026
ColonAtlas; SNU1460
Encyclopedic resources Wikidata; Q54955116
Gene expression databases GEO; GSM1448158
Polymorphism and mutation databases Cosmic; 1322291
IARC_TP53; 28478
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25