ID   SNU-1460
AC   CVCL_5026
SY   SNU1460
DR   cancercelllines; CVCL_5026
DR   ColonAtlas; SNU1460
DR   Cosmic; 1322291
DR   GEO; GSM1448158
DR   IARC_TP53; 28478
DR   KCLB; 01460
DR   Wikidata; Q54955116
RX   PubMed=20176655;
RX   PubMed=25926053;
RX   PubMed=31228769;
CC   Part of: Seoul National University (SNU) cell line collection.
CC   Population: Korean.
CC   Doubling time: 67 hours (PubMed=20176655); 48 hours (PubMed=31228769).
CC   Microsatellite instability: Stable (MSS) (PubMed=20176655; PubMed=25926053).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
ST   Source(s): KCLB=01460; PubMed=20176655; PubMed=25926053; PubMed=31228769; Technion Genomics Center
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 15
ST   D12S391: 17,19
ST   D13S317: 9,12
ST   D16S539: 10
ST   D18S51: 13
ST   D19S433: 13,14.2
ST   D1S1656: 16,17
ST   D21S11: 30.2,31
ST   D22S1045: 16
ST   D2S1338: 23,24
ST   D2S441: 11
ST   D3S1358: 15,17
ST   D5S818: 11
ST   D7S820: 8,11
ST   D8S1179: 13
ST   FGA: 21,23
ST   Penta D: 10,11
ST   Penta E: 13
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 14,18
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   25Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 27
//
RX   PubMed=20176655; DOI=10.1093/carcin/bgq043;
RA   Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H.,
RA   Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.;
RT   "Establishment and characterization of 13 human colorectal carcinoma
RT   cell lines: mutations of genes and expressions of drug-sensitivity
RT   genes and cancer stem cell markers.";
RL   Carcinogenesis 31:1003-1009(2010).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G.,
RA   Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S.,
RA   Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M.,
RA   Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.;
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//
RX   PubMed=31228769; DOI=10.1016/j.tranon.2019.05.019; PMCID=PMC6600802;
RA   Kim S.-C., Shin R., Seo H.-Y., Kim M., Park J.W., Jeong S.-Y.,
RA   Ku J.-L.;
RT   "Identification of a novel fusion gene, FAM174A-WWC1, in early-onset
RT   colorectal cancer: establishment and characterization of four human
RT   cancer cell lines from early-onset colorectal cancers.";
RL   Transl. Oncol. 12:1185-1195(2019).
//