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Cellosaurus SCC-1-Erl-R (CVCL_4V03)

[Text version]
Cell line name SCC-1-Erl-R
Synonyms Erl-R
Accession CVCL_4V03
Resource Identification Initiative To cite this cell line use: SCC-1-Erl-R (RRID:CVCL_4V03)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:114785; Erlotinib.
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7707 (UM-SCC-1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=19190133; DOI=10.1158/1078-0432.CCR-08-2068; PMCID=PMC2903727
Benavente S., Huang S.-M., Armstrong E.A., Chi A., Hsu K.-T., Wheeler D.L., Harari P.M.
Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells.
Clin. Cancer Res. 15:1585-1592(2009)

Cross-references
Encyclopedic resources Wikidata; Q54952325
Entry history
Entry creation14-Dec-2015
Last entry update30-Jan-2024
Version number13