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Cellosaurus U-343MGa (CVCL_4773)

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Cell line name U-343MGa
Synonyms U-343 MG-A; U-343-MG-A; U343-MG-A; U-343 MGa; U343 MGa; U343MGa; U343
Accession CVCL_4773
Resource Identification Initiative To cite this cell line use: U-343MGa (RRID:CVCL_4773)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Omics: Deep exome analysis.
Derived from site: In situ; Brain, temporal lobe; UBERON=UBERON_0001871.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.11
Native American0
East Asian, North4.21
East Asian, South0
South Asian0
European, North72.65
European, South22.03
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_2050 (GOS-3)CVCL_S472 (U-343MGa 31L)CVCL_S474 (U-343MGa Cl2)
CVCL_S475 (U-343MGa Cl3)
Originate from same individual CVCL_S471 ! U-343MG
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): CLS=300365

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135815,17
D5S81812,13
D7S8209,11
D8S117913,14
D13S3179,13
D16S5399,12
D18S5123
D21S1131,33.2
FGA19,20
Penta D9,10
Penta E10,12
TH016,9.3
TPOX8,9
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=3497714
Nister M., Wedell B., Betsholtz C., Bywater-Ekegard M., Pettersson M., Westermark B., Mark J.
Evidence for progressional changes in the human malignant glioma line U-343 MGa: analysis of karyotype and expression of genes encoding the subunit chains of platelet-derived growth factor.
Cancer Res. 47:4953-4960(1987)

DOI=10.1016/B978-0-12-333530-2.50005-8
Nister M., Westermark B.
Human glioma cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York; USA (1994)

PubMed=10709103; DOI=10.1002/(SICI)1097-0215(20000315)85:6<819::AID-IJC15>3.0.CO;2-Q
Enblad P., Hesselager G., Bongcam-Rudloff E., Hallin I., Westermark B., Nister M.
Modulation of phenotype and induction of irregular vessels accompany high tumorigenic potential of clonal human glioma cells xenografted to nude-rat brain.
Int. J. Cancer 85:819-828(2000)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) CLS; 300365
Cell line databases/resources CLO; CLO_0009459
CLDB; cl4586
Cell_Model_Passport; SIDM01421
DepMap; ACH-000036
Anatomy/cell type resources BTO; BTO:0003218
Biological sample resources BioSample; SAMN10988401
CRISP screens repositories BioGRID_ORCS_Cell_line; 350
Chemistry resources PharmacoDB; U343_1631_2019
Encyclopedic resources Wikidata; Q54973569
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number25