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Cellosaurus OVCAR-10 (CVCL_4377)

[Text version]
Cell line name OVCAR-10
Synonyms NIH:OVCAR-10; OVCAR10
Accession CVCL_4377
Resource Identification Initiative To cite this cell line use: OVCAR-10 (RRID:CVCL_4377)
Comments Doubling time: 32.31 hours (JWGray panel).
Omics: Transcriptome analysis by microarray.
Disease Ovarian carcinoma (NCIt: C4908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2307530; DOI=10.1002/ijc.2910450306
Schilder R.J., Hall L., Monks A., Handel L.M., Fornace A.J. Jr., Ozols R.F., Fojo A.T., Hamilton T.C.
Metallothionein gene expression and resistance to cisplatin in human ovarian cancer.
Int. J. Cancer 45:416-422(1990)

PubMed=1348364; DOI=10.1073/pnas.89.7.3070; PMCID=PMC48805
Godwin A.K., Meister A., O'Dwyer P.J., Huang C.-S., Hamilton T.C., Anderson M.E.
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.
Proc. Natl. Acad. Sci. U.S.A. 89:3070-3074(1992)

PubMed=9041185
Johnson S.W., Laub P.B., Beesley J.S., Ozols R.F., Hamilton T.C.
Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in unrelated human ovarian cancer cell lines.
Cancer Res. 57:850-856(1997)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023
Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S., Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G., Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J., Mills G.B., Hennessy B.T.
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mol. Oncol. 7:567-579(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4377
Encyclopedic resources Wikidata; Q54937003
Experimental variables resources EFO; EFO_0022668
Gene expression databases GEO; GSM185131
GEO; GSM185132
GEO; GSM313703
GEO; GSM711711
GEO; GSM851932
Polymorphism and mutation databases Cosmic; 1102813
Progenetix; CVCL_4377
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number18