ID   OVCAR-10
AC   CVCL_4377
SY   NIH:OVCAR-10; OVCAR10
DR   EFO; EFO_0022668
DR   cancercelllines; CVCL_4377
DR   Cosmic; 1102813
DR   GEO; GSM185131
DR   GEO; GSM185132
DR   GEO; GSM313703
DR   GEO; GSM711711
DR   GEO; GSM851932
DR   Progenetix; CVCL_4377
DR   Wikidata; Q54937003
RX   PubMed=1348364;
RX   PubMed=2307530;
RX   PubMed=9041185;
RX   PubMed=22710073;
RX   PubMed=23415752;
CC   Doubling time: 32.31 hours (JWGray panel).
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C4908; Ovarian carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 18
//
RX   PubMed=1348364; DOI=10.1073/pnas.89.7.3070; PMCID=PMC48805;
RA   Godwin A.K., Meister A., O'Dwyer P.J., Huang C.-S., Hamilton T.C.,
RA   Anderson M.E.;
RT   "High resistance to cisplatin in human ovarian cancer cell lines is
RT   associated with marked increase of glutathione synthesis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:3070-3074(1992).
//
RX   PubMed=2307530; DOI=10.1002/ijc.2910450306;
RA   Schilder R.J., Hall L., Monks A., Handel L.M., Fornace A.J. Jr.,
RA   Ozols R.F., Fojo A.T., Hamilton T.C.;
RT   "Metallothionein gene expression and resistance to cisplatin in human
RT   ovarian cancer.";
RL   Int. J. Cancer 45:416-422(1990).
//
RX   PubMed=9041185;
RA   Johnson S.W., Laub P.B., Beesley J.S., Ozols R.F., Hamilton T.C.;
RT   "Increased platinum-DNA damage tolerance is associated with cisplatin
RT   resistance and cross-resistance to various chemotherapeutic agents in
RT   unrelated human ovarian cancer cell lines.";
RL   Cancer Res. 57:850-856(1997).
//
RX   PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677;
RA   Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K.,
RA   Lessey B.A., Jordan V.C., Bradford A.P.;
RT   "DNA profiling analysis of endometrial and ovarian cell lines reveals
RT   misidentification, redundancy and contamination.";
RL   Gynecol. Oncol. 127:241-248(2012).
//
RX   PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023;
RA   Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S.,
RA   Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G.,
RA   Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J.,
RA   Mills G.B., Hennessy B.T.;
RT   "BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one
RT   functionally deleterious BRCA1 mutation.";
RL   Mol. Oncol. 7:567-579(2013).
//