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Cellosaurus TOV-2223 (CVCL_4063)

[Text version]
Cell line name TOV-2223
Synonyms TOV-2223G; TOV2223G
Accession CVCL_4063
Resource Identification Initiative To cite this cell line use: TOV-2223 (RRID:CVCL_4063)
Comments Doubling time: 2.6 +- 0.7 days (PubMed=18507860).
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 89Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission; PubMed=22585861

Markers:
AmelogeninX
CSF1PO12
D2S133818,20
D3S135815,16
D5S81812
D7S82012
D8S117913
D13S31711
D16S53910,15
D18S5116
D19S43313,15
D21S1130,31
FGA20,24
TH016,9
TPOX11
vWA17,19

Run an STR similarity search on this cell line
Web pages http://dpsc.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=TOV-2223G
Publications

PubMed=18507860; DOI=10.1186/1471-2407-8-152; PMCID=PMC2467432
Ouellet V., Zietarska M., Portelance L., Lafontaine J., Madore J., Puiffe M.-L., Arcand S.L., Shen Z., Hebert J., Tonin P.N., Provencher D.M., Mes-Masson A.-M.
Characterization of three new serous epithelial ovarian cancer cell lines.
BMC Cancer 8:152.1-152.18(2008)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K., Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.-Y., van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J., Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P., Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L., Rottapel R., Neel B.G., Moffat J.
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028
Medrano M., Communal L., Brown K.R., Iwanicki M., Normand J., Paterson J., Sircoulomb F., Krzyzanowski P.M., Novak M., Doodnauth S.A., Suarez Saiz F.J., Cullis J., Al-awar R., Neel B.G., McPherson J., Drapkin R.I., Ailles L., Mes-Masson A.-M., Rottapel R.
Interrogation of functional cell-surface markers identifies CD151 dependency in high-grade serous ovarian cancer.
Cell Rep. 18:2343-2358(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4063
Encyclopedic resources Wikidata; Q54972809
Gene expression databases GEO; GSM2475009
Polymorphism and mutation databases Cosmic; 1122316
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17