ID   TOV-2223
AC   CVCL_4063
SY   TOV-2223G; TOV2223G
DR   cancercelllines; CVCL_4063
DR   Cosmic; 1122316
DR   GEO; GSM2475009
DR   Wikidata; Q54972809
RX   PubMed=18507860;
RX   PubMed=22585861;
RX   PubMed=28273451;
WW   http://dpsc.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=TOV-2223G
CC   Doubling time: 2.6 +- 0.7 days (PubMed=18507860).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp53Ter (c.159G>A); ClinVar=VCV000420659; Zygosity=Unspecified (PubMed=18507860; PubMed=28273451).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
ST   Source(s): Direct_author_submission; PubMed=22585861
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11
ST   D16S539: 10,15
ST   D18S51: 16
ST   D19S433: 13,15
ST   D21S11: 30,31
ST   D2S1338: 18,20
ST   D3S1358: 15,16
ST   D5S818: 12
ST   D7S820: 12
ST   D8S1179: 13
ST   FGA: 20,24
ST   TH01: 6,9
ST   TPOX: 11
ST   vWA: 17,19
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   89Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=18507860; DOI=10.1186/1471-2407-8-152; PMCID=PMC2467432;
RA   Ouellet V., Zietarska M., Portelance L., Lafontaine J., Madore J.,
RA   Puiffe M.-L., Arcand S.L., Shen Z., Hebert J., Tonin P.N.,
RA   Provencher D.M., Mes-Masson A.-M.;
RT   "Characterization of three new serous epithelial ovarian cancer cell
RT   lines.";
RL   BMC Cancer 8:152.1-152.18(2008).
//
RX   PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396;
RA   Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K.,
RA   Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.-Y.,
RA   van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J.,
RA   Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P.,
RA   Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L.,
RA   Rottapel R., Neel B.G., Moffat J.;
RT   "Essential gene profiles in breast, pancreatic, and ovarian cancer
RT   cells.";
RL   Cancer Discov. 2:172-189(2012).
//
RX   PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028;
RA   Medrano M., Communal L., Brown K.R., Iwanicki M., Normand J.,
RA   Paterson J., Sircoulomb F., Krzyzanowski P.M., Novak M., Doodnauth S.A.,
RA   Suarez Saiz F.J., Cullis J., Al-awar R., Neel B.G., McPherson J.,
RA   Drapkin R.I., Ailles L., Mes-Masson A.-M., Rottapel R.;
RT   "Interrogation of functional cell-surface markers identifies CD151
RT   dependency in high-grade serous ovarian cancer.";
RL   Cell Rep. 18:2343-2358(2017).
//