Cell line name |
SCC-12 |
Synonyms |
SCC 12; SCC12 |
Accession |
CVCL_4026 |
Resource Identification Initiative |
To cite this cell line use: SCC-12 (RRID:CVCL_4026) |
Comments |
Derived from site: In situ; Face, skin; UBERON=UBERON_1000021. |
Sequence variations |
- Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Leu; Zygosity=Unspecified (PubMed=11992403).
- Mutation; HGNC; 11998; TP53; Simple; p.Val216Gly (c.647T>G); ClinVar=VCV000376671; Zygosity=Unspecified (PubMed=11992403).
|
Disease |
Skin squamous cell carcinoma (NCIt: C4819) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Children:
|
Sex of cell |
Male |
Age at sampling |
60Y |
Category |
Cancer cell line |
Web pages |
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/s/cell-lines-detail-322.html |
Publications | PubMed=7214336 Rheinwald J.G., Beckett M.A. Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas. Cancer Res. 41:1657-1663(1981) PubMed=3360658; DOI=10.1016/0360-3016(88)90013-2 Weichselbaum R.R., Beckett M.A., Dahlberg W.K., Dritschilo A. Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones. Int. J. Radiat. Oncol. Biol. Phys. 14:907-912(1988) DOI=10.1016/B978-0-12-333530-2.50007-1 Carey T.E. Head and neck tumor cell lines. (In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York; USA (1994) PubMed=11992403; DOI=10.1002/ijc.10321 Popp S., Waltering S., Herbst C., Moll I., Boukamp P. UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas. Int. J. Cancer 99:352-360(2002) PubMed=17312569; DOI=10.1002/hed.20478 Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y. Head and neck squamous cell carcinoma cell lines: established models and rationale for selection. Head Neck 29:163-188(2007) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_4026
IGRhCellID; SCC12%20GSE9585
|
Encyclopedic resources |
Wikidata; Q54952327
|
Polymorphism and mutation databases |
Cosmic; 740989
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 30-Jan-2024 |
Version number | 16 |
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