Cellosaurus cell line RT4-D6P2T (CVCL

Cellosaurus RT4-D6P2T (CVCL_4006)

[Text version]

Cell line name

RT4-D6P2T

Synonyms

RT4-D6-P2T; D6P2T

Accession

CVCL_4006

Resource Identification Initiative

To cite this cell line use: RT4-D6P2T (RRID:CVCL_4006)

Comments

Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: In situ; Peripheral nervous system, sciatic nerve; UBERON=UBERON_0001322.
Cell type: Schwann cell; CL=CL_0002573.

Disease

Rat malignant schwannoma (NCIt: C60465)

Species of origin

Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: BDIX; RS=RS:0000091.

Hierarchy

Parent: CVCL_6E50 (RT4-D6)
Children:

CVCL_D3XZ (RT4 NF2.17 #6)	CVCL_D3Y0 (RT4 NF2.17 #8)	CVCL_D3Y1 (RT4 NF2.E106G #27)
CVCL_D3Y2 (RT4 NF2.K413E #4)	CVCL_D3Y3 (RT4 NF2.K413E #8)	CVCL_D3Y5 (RT4 NF2.L64P #10)
CVCL_D3Y4 (RT4 NF2.L64P #7)	CVCL_D3Y6 (RT4 NF2.Q538P #8)	CVCL_D3XY (RT4-54)
CVCL_JK04 (RT4-67)

Category

Cancer cell line

Publications

PubMed=2824698; DOI=10.1111/j.1471-4159.1987.tb02453.x
Bansal R., Pfeiffer S.E.
Regulated galactolipid synthesis and cell surface expression in Schwann cell line D6P2T.
J. Neurochem. 49:1902-1911(1987)

PubMed=11316791; DOI=10.1101/gad.189601; PMCID=PMC312675
Morrison H., Sherman L.S., Legg J., Banine F., Isacke C., Haipek C.A., Gutmann D.H., Ponta H., Herrlich P.
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44.
Genes Dev. 15:968-980(2001)

PubMed=12210843; DOI=10.1002/jnr.10327
Hai M., Muja N., de Vries G.H., Quarles R.H., Patel P.I.
Comparative analysis of Schwann cell lines as model systems for myelin gene transcription studies.
J. Neurosci. Res. 69:497-508(2002)

Cross-references

Cell line collections (Providers)

ATCC; CRL-2768
BCRC; 60508
BCRJ; 0399
ECACC; 93011415

Cell line databases/resources

CLO; CLO_0008893
CLDB; cl4200

Anatomy/cell type resources

BTO; BTO_0001205

Encyclopedic resources

Wikidata; Q54951363

Experimental variables resources

EFO; EFO_0022778

Proteomic databases