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Cellosaurus A818-4 (CVCL_3892)

[Text version]
Cell line name A818-4
Synonyms A-818-4; A 818-4; A818.4; A818 4; A8184; 818-4; 818_4; 818.4; 8184
Accession CVCL_3892
Secondary accession CVCL_0128
Resource Identification Initiative To cite this cell line use: A818-4 (RRID:CVCL_3892)
Comments Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3890 (A818)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=1764370; DOI=10.1038/bjc.1991.467; PMCID=PMC1977874
Barton C.M., Staddon S.L., Hughes C.M., Hall P.A., O'Sullivan C., Kloppel G., Theis B., Russell R.C.G., Neoptolemos J., Williamson R.C.N., Lane D.P., Lemoine N.R.
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.
Br. J. Cancer 64:1076-1082(1991)

PubMed=1906154
Kalthoff H., Roeder C., Humburg I., Thiele H.-G., Greten H., Schmiegel W.H.
Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells.
Oncogene 6:1015-1021(1991)

PubMed=8426738
Kalthoff H., Schmiegel W.H., Roeder C., Kasche D., Schmidt A., Lauer G., Thiele H.-G., Honold G., Pantel K., Riethmuller G., Scherer E., Maurer J., Maacke H., Deppert W.
p53 and K-RAS alterations in pancreatic epithelial cell lesions.
Oncogene 8:289-298(1993)

PubMed=8430098; DOI=10.1073/pnas.90.3.863; PMCID=PMC45770
Schmiegel W.H., Roeder C., Schmielau J., Rodeck U., Kalthoff H.
Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 90:863-867(1993)

PubMed=9472115; DOI=10.3892/ijo.12.3.717
Muller C., Grosse Bockhorn A.C., Klusmeier S., Kiehl M., Roeder C., Kalthoff H., Koch O.M.
Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis.
Int. J. Oncol. 12:717-723(1998)

PubMed=10415853; DOI=10.1111/j.1749-6632.1999.tb09512.x
Lehnert L., Trost H., Schmiegel W.H., Roeder C., Kalthoff H.
Hollow-spheres: a new model for analyses of differentiation of pancreatic duct epithelial cells.
Ann. N. Y. Acad. Sci. 880:83-93(1999)

PubMed=11787853; DOI=10.1007/s004280100474
Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr J.-M., Scarpa A.
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12692724; DOI=10.1007/s00428-003-0784-4
Sipos B., Moser S., Kalthoff H., Torok V., Lohr J.-M., Kloppel G.
A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform.
Virchows Arch. 442:444-452(2003)

Cross-references
Cell line databases/resources MCCL; MCC:0000020
cancercelllines; CVCL_3892
Encyclopedic resources Wikidata; Q54607225
Polymorphism and mutation databases Cosmic; 710850
Cosmic; 736267
Cosmic; 808168
Cosmic; 933525
Cosmic; 1108342
Cosmic; 1320466
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19