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Cellosaurus FHC (CVCL_3688)

[Text version]
Cell line name FHC
Synonyms Fetal Human Colon
Accession CVCL_3688
Resource Identification Initiative To cite this cell line use: FHC (RRID:CVCL_3688)
Comments Characteristics: Forms solid tumors after transplantation into SCID mice.
Doubling time: ~62 hours (PubMed=6519668).
Karyotypic information: Is hypotriploid, has >20 copies of the 8q23~8q24.3 region containing MYC (PubMed=20193843).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Fetal colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 13FW
Category Spontaneously immortalized cell line
STR profile Source(s): AddexBio=P0009022/4980; ATCC=CRL-1831

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,20
D3S135816,18
D5S81812,13
D7S8208,12
D8S117914,17
D13S31712,13
D16S5399,11
D18S5115,17
D19S43313,14.2
D21S1128,29
FGA21,24.3
Penta D9,13
Penta E7,14
TH016,9.3
TPOX8,11
vWA16

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Publications

PubMed=6519668; DOI=10.1007/BF02619632
Siddiqui K.M., Chopra D.P.
Primary and long term epithelial cell cultures from human fetal normal colonic mucosa.
In Vitro 20:859-868(1984)

PubMed=20193843; DOI=10.1016/j.cancergencyto.2009.11.009
Soucek K., Gajduskova P., Brazdova M., Hyzd'alova M., Koci L., Vydra D., Trojanec R., Pernicova Z., Lentvorska L., Hajduch M., Hofmanova J., Kozubik A.
Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation.
Cancer Genet. Cytogenet. 197:107-116(2010)

Cross-references
Cell line collections (Providers) AddexBio; P0009022/4980
ATCC; CRL-1831
KCB; KCB 2017068YJ
KCB; KCB 2018026YJ
Cell line databases/resources CLO; CLO_0003236
CCRID; 5301HUM-KCB18026YJ
Anatomy/cell type resources BTO; BTO_0003808
Biological sample resources BioSample; SAMN03471253
Chemistry resources ChEMBL-Cells; CHEMBL3308603
ChEMBL-Targets; CHEMBL614654
PubChem_Cell_line; CVCL_3688
Encyclopedic resources Wikidata; Q54834869
Gene expression databases GEO; GSM1448155
Polymorphism and mutation databases IARC_TP53; 28522
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22