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Cellosaurus BJ [Human fibroblast] (CVCL_3653)

[Text version]
Cell line name BJ [Human fibroblast]
Synonyms FF-WT-BJ; BJ1
Accession CVCL_3653
Resource Identification Initiative To cite this cell line use: BJ [Human fibroblast] (RRID:CVCL_3653)
Comments Part of: ENCODE project common cell types; tier 3.
Part of: Human Protein Atlas, Cell Atlas panel.
Population: Caucasian.
Senescence: Senesces at 72 PDL. Has a long lifespan in comparison with other normal human fibroblast cell lines (ATCC=CRL-2522).
Omics: Genomics; ChIP-seq; CTCF.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; DNA methylation analysis.
Omics: Proteomics; Expression; Large antibody panel staining analysis.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C243 (246G1)CVCL_C244 (246G3)CVCL_C245 (246G4)
CVCL_C246 (246G5)CVCL_C247 (246G6)CVCL_DQ33 (346D1)
CVCL_DQ34 (346E1)CVCL_DQ35 (346E2)CVCL_DQ36 (346F1)
CVCL_DQ37 (363G1)CVCL_VG15 (4BJ1)CVCL_VG16 (5B1)
CVCL_VG17 (7B1)CVCL_VG18 (7B6)CVCL_C623 (B12-11)
CVCL_C620 (B12-2)CVCL_C621 (B12-3)CVCL_C622 (B12-6)
CVCL_C624 (B124-1)CVCL_C626 (B124-10)CVCL_C627 (B124-13)
CVCL_C625 (B124-2)CVCL_A4YN (BGUi015-A)CVCL_X732 (BJ epi iPS-C)
CVCL_6D12 (BJ hiPSC #11)CVCL_6D13 (BJ hiPSC #12)CVCL_6D14 (BJ hiPSC #5)
CVCL_6D15 (BJ hiPSC #8)CVCL_A4QM (BJ iPSC clone 1)CVCL_A4QN (BJ iPSC clone 2)
CVCL_A4QP (BJ iPSC clone 3)CVCL_X737 (BJ RiPS-A)CVCL_X738 (BJ RiPS-D)
CVCL_X739 (BJ RiPS-E)CVCL_X740 (BJ SiPS-C)CVCL_X741 (BJ SiPS-D)
CVCL_C922 (BJ-RiPS-1.1)CVCL_C923 (BJ-RiPS-1.2)CVCL_C8QN (BJ-TERT)
CVCL_C924 (BJ-RiPS-1.3)CVCL_6573 (BJ1-hTERT)CVCL_C921 (BJ1-iPS1)
CVCL_V235 (BJ1-iPS3)CVCL_0G92 (BJC)CVCL_0G93 (BJD)
CVCL_VU02 (BJFF.6)CVCL_YR24 (CRTDi005-A)CVCL_YR25 (CRTDi005-B)
CVCL_ZI69 (CTRL-iPSC)CVCL_0G85 (eWT-BJ2)CVCL_0G86 (eWT-BJ4)
CVCL_B3T9 (HHUUKDi009-A)CVCL_QX15 (HNL1)CVCL_RL51 (HNL2)
CVCL_RL52 (HNL4)CVCL_RL53 (HNL5)CVCL_RL54 (HNL6)
CVCL_RL55 (HNLp)CVCL_C430 (IPS(Foreskin)-1)CVCL_C431 (IPS(Foreskin)-2)
CVCL_C432 (IPS(Foreskin)-3)CVCL_C433 (IPS(Foreskin)-4)CVCL_YT30 (ISFi001-A)
CVCL_A8SS (ISFi002-A)CVCL_ZZ36 (KKUi001-A)CVCL_C1U7 (KULi003-A)
CVCL_A8MM (MILi001-A)CVCL_B5IQ (MILi001-B)CVCL_B5IR (MILi001-C)
CVCL_ZJ15 (MPIi005-A)CVCL_YX99 (RCSIi001-A)CVCL_VT49 (REGUi001-A)
CVCL_VT50 (REGUi002-A)CVCL_RL56 (T10 [Human iPSC])CVCL_RL57 (T11 [Human ESC])
CVCL_C1WY (UBi005-A)CVCL_E5HD (UCH-HF-12)CVCL_E5HE (UCH-HF-13)
CVCL_E5HF (UCH-HF-47)CVCL_E5HG (UCH-HF-63)CVCL_E5HH (UCH-HF-121)
CVCL_YR26 (UNIPDi004-A)CVCL_YR27 (UNIPDi004-B)CVCL_A5CE (UNIPDi007-A)
CVCL_D0PB (UTUi001-A)CVCL_D0PC (UTUi001-B)CVCL_D0PD (UTUi001-C)
Sex of cell Male
Age at sampling <1M
Category Finite cell line
STR profile Source(s): ATCC=CRL-2522; CLS=305222; PubMed=29444910

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133816,20
D3S135814,16
D5S81812
D7S82011,12
D8S11799,11
D13S3178,9
D16S5399,13
D18S5117,19
D19S43314
D21S1129
FGA22,23
Penta D12,13
Penta E7,17
TH017,8
TPOX10,11
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ENCODE; -; http://genome.ucsc.edu/ENCODE/protocols/cell/human/BJ_Stam_protocol.pdf
Info; HPA; -; https://www.proteinatlas.org/learn/cellines
Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=67
Publications

PubMed=12554677; DOI=10.1093/hmg/ddg023
Tchirkov A., Lansdorp P.M.
Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia.
Hum. Mol. Genet. 12:227-232(2003)

PubMed=23325432; DOI=10.1101/gr.147942.112; PMCID=PMC3589544
Varley K.E., Gertz J., Bowling K.M., Parker S.L., Reddy T.E., Pauli-Behn F., Cross M.K., Williams B.A., Stamatoyannopoulos J.A., Crawford G.E., Absher D.M., Wold B.J., Myers R.M.
Dynamic DNA methylation across diverse human cell lines and tissues.
Genome Res. 23:555-567(2013)

PubMed=29444910; DOI=10.1530/ERC-17-0445; PMCID=PMC5827037
Hofving T., Arvidsson Y., Almobarak B., Inge L., Pfragner R., Persson M., Stenman G., Kristiansson E., Johanson V., Nilsson O.
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
Endocr. Relat. Cancer 25:367-380(2018)

Cross-references
Cell line collections (Providers) AddexBio; P0012005/4972
ATCC; CRL-2522
CLS; 305222
Ubigene; YC-C080
Cell line databases/resources CLO; CLO_0001980
Cell_Model_Passport; SIDM01891
Lonza; 723
SKIP; SKIP001154
TOKU-E; 672
Anatomy/cell type resources BTO; BTO_0003807
Biological sample resources ENCODE; ENCBS070WLP
ENCODE; ENCBS074ENC
ENCODE; ENCBS137RRI
ENCODE; ENCBS170GUW
ENCODE; ENCBS198NMJ
ENCODE; ENCBS335XLL
ENCODE; ENCBS339MSO
ENCODE; ENCBS488ZLU
ENCODE; ENCBS610AAA
ENCODE; ENCBS611AAA
ENCODE; ENCBS612AAA
ENCODE; ENCBS613AAA
ENCODE; ENCBS614AAA
ENCODE; ENCBS615AAA
ENCODE; ENCBS616AAA
ENCODE; ENCBS628EGC
ENCODE; ENCBS683XYV
ENCODE; ENCBS693PNC
ENCODE; ENCBS753AAA
ENCODE; ENCBS754AAA
ENCODE; ENCBS772THG
ENCODE; ENCBS815JWZ
ENCODE; ENCBS911DVL
ENCODE; ENCBS935PZD
CRISP screens repositories BioGRID_ORCS_Cell_line; 1125
Chemistry resources ChEMBL-Cells; CHEMBL3307781
ChEMBL-Targets; CHEMBL614358
PubChem_Cell_line; CVCL_3653
Encyclopedic resources Wikidata; Q54796903
Experimental variables resources EFO; EFO_0002779
Gene expression databases GEO; GSM248213
GEO; GSM248214
GEO; GSM472898
GEO; GSM472924
GEO; GSM472925
GEO; GSM579886
GEO; GSM579887
GEO; GSM736518
GEO; GSM736596
GEO; GSM749677
GEO; GSM749752
GEO; GSM749770
GEO; GSM923444
GEO; GSM945178
GEO; GSM945204
GEO; GSM945207
GEO; GSM945235
GEO; GSM2988896
GEO; GSM7701416
GEO; GSM7701417
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number35