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Cellosaurus NIT-1 (CVCL_3561)

[Text version]
Cell line name NIT-1
Synonyms NIT1
Accession CVCL_3561
Resource Identification Initiative To cite this cell line use: NIT-1 (RRID:CVCL_3561)
Comments Characteristics: Secretes insulin.
Doubling time: 49.1 hours (Note=At 18th passage) (PubMed=1647994).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NOD/Lt-Tg(RIPTag)1Lt transgenic.
Hierarchy Children:
CVCL_E1A6 (Ubigene NIT-1 Esr1 KO)CVCL_E1A7 (Ubigene NIT-1 Fto KO)CVCL_E1A8 (Ubigene NIT-1 Ythdc2 KO)
Sex of cell Female
Age at sampling 10W
Category Transformed cell line
Publications

PubMed=1647994; DOI=10.2337/diab.40.7.842
Hamaguchi K., Gaskins H.R., Leiter E.H.
NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse.
Diabetes 40:842-849(1991)

PubMed=8697299
Poitout V., Olson L.K., Robertson R.P.
Insulin-secreting cell lines: classification, characteristics and potential applications.
Diabetes Metab. 22:7-14(1996)

Cross-references
Cell line collections (Providers) ATCC; CRL-2055
BCRC; 60452
IZSLER; BS TCL 192
Cell line databases/resources CLO; CLO_0008175
Encyclopedic resources Wikidata; Q54930633
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number17