ID   NIT-1
AC   CVCL_3561
SY   NIT1
DR   CLO; CLO_0008175
DR   ATCC; CRL-2055
DR   BCRC; 60452
DR   IZSLER; BS TCL 192
DR   Wikidata; Q54930633
RX   PubMed=1647994;
RX   PubMed=8697299;
CC   Characteristics: Secretes insulin.
CC   Doubling time: 49.1 hours (Note=At 18th passage) (PubMed=1647994).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Pancreatic beta cell; CL=CL_0000169.
CC   Breed/subspecies: NOD/Lt-Tg(RIPTag)1Lt transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   10W
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 17
//
RX   PubMed=1647994; DOI=10.2337/diab.40.7.842;
RA   Hamaguchi K., Gaskins H.R., Leiter E.H.;
RT   "NIT-1, a pancreatic beta-cell line established from a transgenic
RT   NOD/Lt mouse.";
RL   Diabetes 40:842-849(1991).
//
RX   PubMed=8697299;
RA   Poitout V., Olson L.K., Robertson R.P.;
RT   "Insulin-secreting cell lines: classification, characteristics and
RT   potential applications.";
RL   Diabetes Metab. 22:7-14(1996).
//