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Cellosaurus LA-4 [Mouse lung adenoma] (CVCL_3535)

[Text version]
Cell line name LA-4 [Mouse lung adenoma]
Synonyms LA 4; LA4
Accession CVCL_3535
Resource Identification Initiative To cite this cell line use: LA-4 [Mouse lung adenoma] (RRID:CVCL_3535)
Comments Karyotypic information: 85 to 93 chromosomes; hyper-tetraploid karyotype (PubMed=34881029).
Transformant: ChEBI; CHEBI_17967; Urethane.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Disease Adenoma of the mouse pulmonary system (NCIt: C21762)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/He.
Sex of cell Female
Age at sampling 28W
Category Cancer cell line
Publications

PubMed=167947
Stoner G.D., Kikkawa Y., Kniazeff A.J., Miyai K., Wagner R.M.
Clonal isolation of epithelial cells from mouse lung adenoma.
Cancer Res. 35:2177-2185(1975)

PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222
Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.
Cultured cell lines for research on pulmonary physiology available through the American Type Culture Collection.
Am. Rev. Respir. Dis. 125:222-232(1982)

PubMed=9347924; DOI=10.1016/S0300-483X(97)00108-X
Malkinson A.M., Dwyer-Nield L.D., Rice P.L., Dinsdale D.
Mouse lung epithelial cell lines -- tools for the study of differentiation and the neoplastic phenotype.
Toxicology 123:53-100(1997)

PubMed=34881029; DOI=10.3892/mco.2021.2440; PMCID=PMC8647198
Azawi S., Balachandran M., Kramer F., Kankel S., Rincic M., Liehr T.
Molecular cytogenetic characterization of the urethane-induced murine lung cell line LA-4 as a model for human squamous cell lung cancer.
Mol. Clin. Oncol. 16:9.1-9.5(2022)

Cross-references
Cell line collections (Providers) ATCC; CCL-196
BCRC; 60239
ECACC; 90040512
KCLB; 10196
Cell line databases/resources CLO; CLO_0007229
CLDB; cl3163
Encyclopedic resources Wikidata; Q54901867
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16