ID   LA-4 [Mouse lung adenoma]
AC   CVCL_3535
SY   LA 4; LA4
DR   CLO; CLO_0007229
DR   CLDB; cl3163
DR   ATCC; CCL-196
DR   BCRC; 60239
DR   ECACC; 90040512
DR   KCLB; 10196
DR   Wikidata; Q54901867
RX   PubMed=167947;
RX   PubMed=7065527;
RX   PubMed=9347924;
RX   PubMed=34881029;
CC   Karyotypic information: 85 to 93 chromosomes; hyper-tetraploid karyotype (PubMed=34881029).
CC   Transformant: ChEBI; CHEBI_17967; Urethane.
CC   Omics: Array-based CGH.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Breed/subspecies: A/He.
DI   NCIt; C21762; Adenoma of the mouse pulmonary system
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   28W
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=167947;
RA   Stoner G.D., Kikkawa Y., Kniazeff A.J., Miyai K., Wagner R.M.;
RT   "Clonal isolation of epithelial cells from mouse lung adenoma.";
RL   Cancer Res. 35:2177-2185(1975).
//
RX   PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222;
RA   Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.;
RT   "Cultured cell lines for research on pulmonary physiology available
RT   through the American Type Culture Collection.";
RL   Am. Rev. Respir. Dis. 125:222-232(1982).
//
RX   PubMed=9347924; DOI=10.1016/S0300-483X(97)00108-X;
RA   Malkinson A.M., Dwyer-Nield L.D., Rice P.L., Dinsdale D.;
RT   "Mouse lung epithelial cell lines -- tools for the study of
RT   differentiation and the neoplastic phenotype.";
RL   Toxicology 123:53-100(1997).
//
RX   PubMed=34881029; DOI=10.3892/mco.2021.2440; PMCID=PMC8647198;
RA   Azawi S., Balachandran M., Kramer F., Kankel S., Rincic M., Liehr T.;
RT   "Molecular cytogenetic characterization of the urethane-induced murine
RT   lung cell line LA-4 as a model for human squamous cell lung cancer.";
RL   Mol. Clin. Oncol. 16:9.1-9.5(2022).
//