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Cellosaurus J558 (CVCL_3529)

[Text version]
Cell line name J558
Accession CVCL_3529
Resource Identification Initiative To cite this cell line use: J558 (RRID:CVCL_3529)
Comments Problematic cell line: Potentially contaminated. The stock distributed by ATCC (TIB-6) has a STR profile that matches at 95% with that of BALB/3T3 clone A31 (Cellosaurus=CVCL_0184). As this is the parent cell line to a cell line J558L (Cellosaurus=CVCL_3949) which is used a fusion cell line for the production of hybridomas ICLAC is currently investigating if authentic stocks of J558 still exist.
Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Monoclonal antibody isotype: IgA, lambda.
Monoclonal antibody target: ChEBI; CHEBI_52071; Dextran.
Cell type: B-cell; CL=CL_0000236.
Disease Mouse plasma cell myeloma (NCIt: C125417)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Children:
CVCL_E3HM (HyCyte J558-Luc)CVCL_3949 (J558L)
Category Cancer cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-116
Mouse STR 1-217
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-221.3
Mouse STR 5-514
Mouse STR 6-418
Mouse STR 6-712
Mouse STR 7-125.2
Mouse STR 8-113
Mouse STR 11-217
Mouse STR 12-116
Mouse STR 13-116.2
Mouse STR 15-322.3
Mouse STR 17-216
Mouse STR 18-318
Mouse STR 19-214
Mouse STR X-125

Run an STR similarity search on this cell line
Publications

PubMed=5483159; DOI=10.1038/2281045a0
Weigert M.G., Cesari I.M., Yonkovich S.J., Cohn M.
Variability in the lambda light chain sequences of mouse antibody.
Nature 228:1045-1047(1970)

PubMed=6157734; DOI=10.4049/jimmunol.125.4.1454
Bhoopalam N., Heller P., Meyerstein N., Hall L.
Effect of dextran-S (alpha, 1-3 dextran) on the growth of plasmacytomas MOPC-104E and J558.
J. Immunol. 125:1454-1458(1980)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections (Providers) ATCC; TIB-6
Cell line databases/resources CLO; CLO_0007001
Biological sample resources BioSample; SAMN11397662 - Discontinued
Encyclopedic resources Wikidata; Q28243888
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number15