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Cellosaurus PLHC-1 (CVCL_3466)

[Text version]
Cell line name PLHC-1
Synonyms Poeciliopsis Lucida Hepatocellular Carcinoma-1; PLHC-1/wt; PLHC1
Accession CVCL_3466
Resource Identification Initiative To cite this cell line use: PLHC-1 (RRID:CVCL_3466)
Comments Group: Fish cell line.
Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Poeciliopsis lucida hepatocellular carcinoma (NCIt: C134962)
Species of origin Poeciliopsis lucida (Desert topminnow) (NCBI Taxonomy: 56613)
Hierarchy Children:
CVCL_S585 (PLHC-1/dox)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=1868789; DOI=10.1016/0147-6513(91)90072-W
Babich H.J., Rosenberg D.W., Borenfreund E.
In vitro cytotoxicity studies with the fish hepatoma cell line, PLHC-1 (Poeciliopsis lucida).
Ecotoxicol. Environ. Saf. 21:327-336(1991)

PubMed=9734273; DOI=10.1016/S0045-6535(97)10248-X
Huuskonen S.E., Hahn M.E., Lindstrom-Seppa P.
A fish hepatoma cell line (PLHC-1) as a tool to study cytotoxicity and CYP1A induction properties of cellulose and wood chip extracts.
Chemosphere 36:2921-2932(1998)

DOI=10.1016/S1873-0140(05)80005-0
Bols N.C., Dayeh V.R., Lee L.E.J., Schirmer K.
Use of fish cell lines in the toxicology and ecotoxicology of fish Piscine cell lines in environmental toxicology.
(In) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen T.P., Moon T.W. (eds.); pp.43-84; Elsevier; Amsterdam (2005)

PubMed=21392495; DOI=10.1016/j.aquatox.2011.02.005
Zaja R., Loncar J., Popovic M., Smital T.
First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line.
Aquat. Toxicol. 103:53-62(2011)

PubMed=22281180; DOI=10.1016/j.tiv.2012.01.001
Kienzler A., Tronchere X., Devaux A., Bony S.
Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for genotoxicity testing of environmental pollutants by means of a Fpg-modified comet assay.
Toxicol. In Vitro 26:500-510(2012)

DOI=10.3390/fishes7060354
Espinosa-Ruiz C., Mayor-Lafuente J., Esteban M.A.
Mitochondrial metabolism characterization of four different fish cell lines.
Fishes 7:354.1-354.6(2022)

Cross-references
Cell line collections (Providers) ATCC; CRL-2406
Cell line databases/resources CLO; CLO_0008460
Anatomy/cell type resources BTO; BTO:0002331
Encyclopedic resources Wikidata; Q54947578
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number19