ID   PLHC-1
AC   CVCL_3466
SY   Poeciliopsis Lucida Hepatocellular Carcinoma-1; PLHC-1/wt; PLHC1
DR   BTO; BTO:0002331
DR   CLO; CLO_0008460
DR   ATCC; CRL-2406
DR   Wikidata; Q54947578
RX   DOI=10.1016/S1873-0140(05)80005-0;
RX   DOI=10.3390/fishes7060354;
RX   PubMed=1868789;
RX   PubMed=9734273;
RX   PubMed=21392495;
RX   PubMed=22281180;
CC   Group: Fish cell line.
CC   Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C134962; Poeciliopsis lucida hepatocellular carcinoma
OX   NCBI_TaxID=56613; ! Poeciliopsis lucida (Desert topminnow)
SX   Female
AG   Adult
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 19
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RX   DOI=10.1016/S1873-0140(05)80005-0;
RA   Bols N.C., Dayeh V.R., Lee L.E.J., Schirmer K.;
RT   "Use of fish cell lines in the toxicology and ecotoxicology of fish.
RT   Piscine cell lines in environmental toxicology.";
RL   (In) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen T.P., Moon T.W. (eds.); pp.43-84; Elsevier; Amsterdam (2005).
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RX   DOI=10.3390/fishes7060354;
RA   Espinosa-Ruiz C., Mayor-Lafuente J., Esteban M.A.;
RT   "Mitochondrial metabolism characterization of four different fish
RT   cell lines.";
RL   Fishes 7:354.1-354.6(2022).
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RX   PubMed=1868789; DOI=10.1016/0147-6513(91)90072-W;
RA   Babich H.J., Rosenberg D.W., Borenfreund E.;
RT   "In vitro cytotoxicity studies with the fish hepatoma cell line,
RT   PLHC-1 (Poeciliopsis lucida).";
RL   Ecotoxicol. Environ. Saf. 21:327-336(1991).
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RX   PubMed=9734273; DOI=10.1016/S0045-6535(97)10248-X;
RA   Huuskonen S.E., Hahn M.E., Lindstrom-Seppa P.;
RT   "A fish hepatoma cell line (PLHC-1) as a tool to study cytotoxicity
RT   and CYP1A induction properties of cellulose and wood chip extracts.";
RL   Chemosphere 36:2921-2932(1998).
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RX   PubMed=21392495; DOI=10.1016/j.aquatox.2011.02.005;
RA   Zaja R., Loncar J., Popovic M., Smital T.;
RT   "First characterization of fish P-glycoprotein (abcb1) substrate
RT   specificity using determinations of its ATPase activity and
RT   calcein-AM assay with PLHC-1/dox cell line.";
RL   Aquat. Toxicol. 103:53-62(2011).
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RX   PubMed=22281180; DOI=10.1016/j.tiv.2012.01.001;
RA   Kienzler A., Tronchere X., Devaux A., Bony S.;
RT   "Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for
RT   genotoxicity testing of environmental pollutants by means of a
RT   Fpg-modified comet assay.";
RL   Toxicol. In Vitro 26:500-510(2012).
//