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Cellosaurus OX-CO-2 (CVCL_2H53)

[Text version]
Cell line name OX-CO-2
Synonyms OXCO-2; OXCO2
Accession CVCL_2H53
Resource Identification Initiative To cite this cell line use: OX-CO-2 (RRID:CVCL_2H53)
Comments Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A2CH (OX-CO-2 R1 Cetux)CVCL_A2CI (OX-CO-2 R2 Cetux)CVCL_A2CJ (OXCO-2 R3 Cetux)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=25926053

Markers:
AmelogeninX,Y
CSF1PO9,13
D5S81811,12
D7S82010,13
D13S31710,11
D16S53911,12
D21S1130
TH018
TPOX11
vWA17,22

Run an STR similarity search on this cell line
Publications

PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
Bracht K., Nicholls A.M., Liu Y., Bodmer W.F.
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=25623215; DOI=10.1158/1078-0432.CCR-14-2821
Arena S., Bellosillo B., Siravegna G., Martinez A., Canadas I., Lazzari L., Ferruz N., Russo M., Misale S., Gonzalez I., Iglesias M., Gavilan E., Corti G., Hobor S., Crisafulli G., Salido M., Sanchez J., Dalmases A., Bellmunt J., De Fabritiis G., Rovira A., Di Nicolantonio F., Albanell J., Bardelli A., Montagut C.
Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer.
Clin. Cancer Res. 21:2157-2166(2015)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Encyclopedic resources Wikidata; Q54937177
Gene expression databases GEO; GSM1448146
Polymorphism and mutation databases Cosmic; 2841375
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number8