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Cellosaurus AG04659 (CVCL_2B13)

[Text version]
Cell line name AG04659
Synonyms AG_04659; AG4659; GRC#0219
Accession CVCL_2B13
Resource Identification Initiative To cite this cell line use: AG04659 (RRID:CVCL_2B13)
Comments Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
Population: Caucasian.
Senescence: Senesces at 29 PDL (Coriell=AG04659).
Doubling time: 1.7 days (PubMed=12840040).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2B43 ! AG05283
CVCL_2D83 ! AG11243
Sex of cell Male
Age at sampling 65Y
Category Finite cell line
Publications

PubMed=7307581; DOI=10.1159/000131624
Schneider E.L., Monticone R., Smith J., Braunschweiger K., Roberts T.
Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging.
Cytogenet. Cell Genet. 31:40-46(1981)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994)

PubMed=12840040; DOI=10.1101/gr.1289803
Karaman M.W., Houck M.L., Chemnick L.G., Nagpal S., Chawannakul D., Sudano D., Pike B.L., Ho V.V., Ryder O.A., Hacia J.G.
Comparative analysis of gene-expression patterns in human and African great ape cultured fibroblasts.
Genome Res. 13:1619-1630(2003)

PubMed=14662655; DOI=10.1093/hmg/ddh026
Khan S.G., Metin A., Gozukara E.M., Inui H., Shahlavi T., Muniz-Medina V., Baker C.C., Ueda T., Aiken J.R., Schneider T.D., Kraemer K.H.
Two essential splice lariat branchpoint sequences in one intron in a xeroderma pigmentosum DNA repair gene: mutations result in reduced XPC mRNA levels that correlate with cancer risk.
Hum. Mol. Genet. 13:343-352(2004)

PubMed=16081512; DOI=10.1093/carcin/bgi204
Khan S.G., Oh K.-S., Shahlavi T., Ueda T., Busch D.B., Inui H., Emmert S., Imoto K., Muniz-Medina V., Baker C.C., DiGiovanna J.J., Schmidt D., Khadavi A., Metin A., Gozukara E.M., Slor H., Sarasin A., Kraemer K.H.
Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients.
Carcinogenesis 27:84-94(2006)

PubMed=18368133; DOI=10.1038/jid.2008.48
Inui H., Oh K.-S., Nadem C., Ueda T., Khan S.G., Metin A., Gozukara E.M., Emmert S., Slor H., Busch D.B., Baker C.C., DiGiovanna J.J., Tamura D., Seitz C.S., Gratchev A., Wu W.-H., Chung K.Y., Chung H.J., Azizi E., Woodgate R., Schneider T.D., Kraemer K.H.
Xeroderma pigmentosum-variant patients from America, Europe, and Asia.
J. Invest. Dermatol. 128:2055-2068(2008)

Cross-references
Cell line collections (Providers) Coriell; AG04659
Cell line databases/resources CLO; CLO_0034920
Encyclopedic resources Wikidata; Q54610375
Gene expression databases GEO; GSM6348
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number14