ID   AG04659
AC   CVCL_2B13
SY   AG_04659; AG4659; GRC#0219
DR   CLO; CLO_0034920
DR   Coriell; AG04659
DR   GEO; GSM6348
DR   Wikidata; Q54610375
RX   CelloPub=CLPUB00597;
RX   PubMed=7307581;
RX   PubMed=12840040;
RX   PubMed=14662655;
RX   PubMed=16081512;
RX   PubMed=18368133;
CC   Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
CC   Population: Caucasian.
CC   Senescence: Senesces at 29 PDL (Coriell=AG04659).
CC   Doubling time: 1.7 days (PubMed=12840040).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_2B43 ! AG05283
OI   CVCL_2D83 ! AG11243
SX   Male
AG   65Y
CA   Finite cell line
DT   Created: 22-09-15; Last updated: 29-06-23; Version: 14
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RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994).
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RX   PubMed=7307581; DOI=10.1159/000131624;
RA   Schneider E.L., Monticone R., Smith J., Braunschweiger K.I., Roberts T.;
RT   "Skin fibroblast cultures derived from members of the Baltimore
RT   longitudinal study: a new resource for studies of cellular aging.";
RL   Cytogenet. Cell Genet. 31:40-46(1981).
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RX   PubMed=12840040; DOI=10.1101/gr.1289803;
RA   Karaman M.W., Houck M.L., Chemnick L.G., Nagpal S., Chawannakul D.,
RA   Sudano D., Pike B.L., Ho V.V., Ryder O.A., Hacia J.G.;
RT   "Comparative analysis of gene-expression patterns in human and African
RT   great ape cultured fibroblasts.";
RL   Genome Res. 13:1619-1630(2003).
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RX   PubMed=14662655; DOI=10.1093/hmg/ddh026;
RA   Khan S.G., Metin A., Gozukara E.M., Inui H., Shahlavi T.,
RA   Muniz-Medina V., Baker C.C., Ueda T., Aiken J.R., Schneider T.D.,
RA   Kraemer K.H.;
RT   "Two essential splice lariat branchpoint sequences in one intron in a
RT   xeroderma pigmentosum DNA repair gene: mutations result in reduced XPC
RT   mRNA levels that correlate with cancer risk.";
RL   Hum. Mol. Genet. 13:343-352(2004).
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RX   PubMed=16081512; DOI=10.1093/carcin/bgi204;
RA   Khan S.G., Oh K.-S., Shahlavi T., Ueda T., Busch D.B., Inui H.,
RA   Emmert S., Imoto K., Muniz-Medina V., Baker C.C., DiGiovanna J.J.,
RA   Schmidt D., Khadavi A., Metin A., Gozukara E.M., Slor H., Sarasin A.,
RA   Kraemer K.H.;
RT   "Reduced XPC DNA repair gene mRNA levels in clinically normal parents
RT   of xeroderma pigmentosum patients.";
RL   Carcinogenesis 27:84-94(2006).
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RX   PubMed=18368133; DOI=10.1038/jid.2008.48;
RA   Inui H., Oh K.-S., Nadem C., Ueda T., Khan S.G., Metin A., Gozukara E.M.,
RA   Emmert S., Slor H., Busch D.B., Baker C.C., DiGiovanna J.J.,
RA   Tamura D., Seitz C.S., Gratchev A., Wu W.-H., Chung K.Y., Chung H.J.,
RA   Azizi E., Woodgate R., Schneider T.D., Kraemer K.H.;
RT   "Xeroderma pigmentosum-variant patients from America, Europe, and
RT   Asia.";
RL   J. Invest. Dermatol. 128:2055-2068(2008).
//