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Cellosaurus UM-RC-3 (CVCL_2740)

[Text version]
Cell line name UM-RC-3
Synonyms UMRC-3; UMRC3; University of Michigan-Renal Carcinoma-3
Accession CVCL_2740
Resource Identification Initiative To cite this cell line use: UM-RC-3 (RRID:CVCL_2740)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~29 hours (PubMed=4038766).
Omics: Proteomics; PTM; GPI-anchored proteins.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001687; ECACC=08090512

Markers:
AmelogeninX
CSF1PO12
D3S135818
D5S8189,12
D7S8209
D8S117912
D13S3179,12
D16S5399
D18S5113,15
D21S1130.2
FGA22
Penta D13
Penta E11,13
TH019.3
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=4038766; DOI=10.1002/jso.2930280320
Grossman H.B., Wedemeyer G., Ren L.-Q.
Human renal carcinoma: characterization of five new cell lines.
J. Surg. Oncol. 28:237-244(1985)

PubMed=7915601; DOI=10.1038/ng0594-85
Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., Linehan W.M.
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008
Masuishi Y., Kimura Y., Arakawa N., Hirano H.
Identification of glycosylphosphatidylinositol-anchored proteins and omega-sites using TiO2-based affinity purification followed by hydrogen fluoride treatment.
J. Proteomics 139:77-83(2016)

PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930
Masuishi Y., Kimura Y., Arakawa N., Hirano H.
Data for identification of GPI-anchored peptides and omega-sites in cancer cell lines.
Data Brief 7:1302-1305(2016)

Cross-references
Cell line collections (Providers) CancerTools; 160447
ECACC; 08090512 - Discontinued
Ximbio; 160447
Cell line databases/resources cancercelllines; CVCL_2740
DepMap; ACH-001687
Encyclopedic resources Wikidata; Q54990784
Polymorphism and mutation databases Cosmic; 972911
Proteomic databases PRIDE; PXD003105
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23