ID   UM-RC-3
AC   CVCL_2740
SY   UMRC-3; UMRC3; University of Michigan-Renal Carcinoma-3
DR   cancercelllines; CVCL_2740
DR   CancerTools; 160447
DR   Cosmic; 972911
DR   DepMap; ACH-001687
DR   ECACC; 08090512
DR   PRIDE; PXD003105
DR   Wikidata; Q54990784
DR   Ximbio; 160447
RX   PubMed=4038766;
RX   PubMed=7915601;
RX   PubMed=26972028;
RX   PubMed=27141528;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: ~29 hours (PubMed=4038766).
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Leu89His (c.266T>A); ClinVar=VCV000376047; Zygosity=Unspecified (PubMed=7915601).
CC   Omics: GPI-anchored proteins analysis by proteomics.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): DepMap; ECACC
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9,12
ST   D16S539: 9
ST   D18S51: 13,15
ST   D21S11: 30.2
ST   D3S1358: 18
ST   D5S818: 9,12
ST   D7S820: 9
ST   D8S1179: 12
ST   FGA: 22
ST   Penta D: 13
ST   Penta E: 11,13
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16,18
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 19
//
RX   PubMed=4038766; DOI=10.1002/jso.2930280320;
RA   Grossman H.B., Wedemeyer G., Ren L.-Q.;
RT   "Human renal carcinoma: characterization of five new cell lines.";
RL   J. Surg. Oncol. 28:237-244(1985).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008;
RA   Masuishi Y., Kimura Y., Arakawa N., Hirano H.;
RT   "Identification of glycosylphosphatidylinositol-anchored proteins and
RT   omega-sites using TiO2-based affinity purification followed by
RT   hydrogen fluoride treatment.";
RL   J. Proteomics 139:77-83(2016).
//
RX   PubMed=27141528; DOI=10.1016/j.dib.2016.04.001;
RA   Masuishi Y., Kimura Y., Arakawa N., Hirano H.;
RT   "Data for identification of GPI-anchored peptides and omega-sites in
RT   cancer cell lines.";
RL   Data Brief 7:1302-1305(2016).
//