| Cell line name |
HT29/219 |
| Synonyms |
HT-29/219; HT29219 |
| Accession |
CVCL_2521 |
| Secondary accession |
CVCL_6835 |
| Resource Identification Initiative |
To cite this cell line use: HT29/219 (RRID:CVCL_2521) |
| Comments |
Part of: MD Anderson Cell Lines Project. Population: Caucasian. Omics: Proteomics; Expression; Reverse-phase protein array. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
|
| Disease |
Colon adenocarcinoma (NCIt: C4349) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Parent: CVCL_0320 (HT-29) |
| Sex of cell |
Female |
| Age at sampling |
44Y |
| Category |
Cancer cell line |
| STR profile |
Source(s): ECACC=85061109; PubMed=17254797
Markers:| Amelogenin | X |
| CSF1PO | 11 (PubMed=17254797) 11,12 (ECACC=85061109) |
| D3S1358 | 15,17 |
| D5S818 | 11,12 |
| D7S820 | 10 |
| D8S1179 | 10 |
| D13S317 | 11 (PubMed=17254797) 11,12 (ECACC=85061109) |
| D16S539 | 11,12 |
| D18S51 | 13 |
| D21S11 | 28,30 |
| FGA | 19,21 |
| TH01 | 6,9 |
| TPOX | 8,9 |
| vWA | 17,19 |
Run an STR similarity search on this cell line |
| Web pages |
Info; MCLP; -; https://tcpaportal.org/mclp/ |
| Publications | PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001 Shahram Azari, Nahid Ahmadi, Mahmood Jeddi-Tehrani, Fazel Shokri; Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran. Biologicals 35:195-202(2007) PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, Agda Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors Characterization of human cancer cell lines by reverse-phase protein arrays. Cancer Cell 31:225-239(2017) |
| Cross-references |
| Cell line collections (Providers) |
ECACC; 85061109
NCBI_Iran; C154
|
| Cell line databases/resources |
CLO; CLO_0004285
CLDB; cl1758
cancercelllines; CVCL_2521
|
| Anatomy/cell type resources |
BTO; BTO_0002838
|
| Encyclopedic resources |
Wikidata; Q54896595
|
| Entry history |
| Entry creation | 04-Apr-2012 |
| Last entry update | 10-Apr-2025 |
| Version number | 28 |
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