Cellosaurus cell line H103 (CVCL

Cellosaurus H103 (CVCL_2457)

[Text version]

Cell line name

H103

Accession

CVCL_2457

Resource Identification Initiative

To cite this cell line use: H103 (RRID:CVCL_2457)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Karyotypic information: Has lost chromosome Y.
Omics: Deep exome analysis.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly244Cys (c.730G>T); ClinVar=VCV000376599; Zygosity=Homozygous (PubMed=7633286; DepMap=ACH-001346).

Disease

Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

32Y

Category

Cancer cell line

STR profile

Source(s): DepMap=ACH-001346; ECACC=06092001

Markers:

Amelogenin	X
CSF1PO	9,10
D3S1358	17
D5S818	10,11
D7S820	10
D8S1179	12,13
D13S317	12,13
D16S539	11,12
D18S51	15
D21S11	30
FGA	21,23
Penta D	9,11
Penta E	20
TH01	8,9
TPOX	8,9
vWA	14,16

Publications

PubMed=1692339; DOI=10.1002/path.1711600313
Prime S.S., Nixon S.V.R., Crane I.J., Stone A., Matthews J.B., Maitland N.J., Remnant L., Powell S.K., Game S.M., Scully C.
The behaviour of human oral squamous cell carcinoma in cell culture.
J. Pathol. 160:259-269(1990)

PubMed=1744799; DOI=10.1002/path.1711650208
Mutlu S., Matthews J.B., Midda M., Scully C., Prime S.S.
MHC antigen expression in human oral squamous carcinoma cell lines.
J. Pathol. 165:129-136(1991)

PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8
Yeudall W.A., Paterson I.C., Patel V., Prime S.S.
Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.
Eur. J. Cancer B. Oral Oncol. 31:136-143(1995)

Cross-references

Cell line collections (Providers)

CancerTools; 153419
ECACC; 06092001 - Discontinued
Ximbio; 153419

Cell line databases/resources

Cell_Model_Passport; SIDM01568
DepMap; ACH-001346

Chemistry resources

ChEMBL-Cells; CHEMBL4483157
ChEMBL-Targets; CHEMBL4483241
PubChem_Cell_line; CVCL_2457

Encyclopedic resources

Wikidata; Q54871913

Polymorphism and mutation databases

Cosmic; 716673
Cosmic; 916367
Cosmic; 928234

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number