ID   H103
AC   CVCL_2457
DR   CancerTools; 153419
DR   Cell_Model_Passport; SIDM01568
DR   ChEMBL-Cells; CHEMBL4483157
DR   ChEMBL-Targets; CHEMBL4483241
DR   Cosmic; 716673
DR   Cosmic; 916367
DR   Cosmic; 928234
DR   DepMap; ACH-001346
DR   ECACC; 06092001
DR   PubChem_Cell_line; CVCL_2457
DR   Wikidata; Q54871913
DR   Ximbio; 153419
RX   PubMed=1692339;
RX   PubMed=1744799;
RX   PubMed=7633286;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Karyotypic information: Has lost chromosome Y.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly244Cys (c.730G>T); ClinVar=VCV000376599; Zygosity=Homozygous (PubMed=7633286; DepMap=ACH-001346).
CC   Omics: Deep exome analysis.
CC   Discontinued: ECACC; 06092001; true.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
ST   Source(s): DepMap=ACH-001346; ECACC=06092001
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13
ST   D16S539: 11,12
ST   D18S51: 15
ST   D21S11: 30
ST   D3S1358: 17
ST   D5S818: 10,11
ST   D7S820: 10
ST   D8S1179: 12,13
ST   FGA: 21,23
ST   Penta D: 9,11
ST   Penta E: 20
ST   TH01: 8,9
ST   TPOX: 8,9
ST   vWA: 14,16
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   32Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 22
//
RX   PubMed=1692339; DOI=10.1002/path.1711600313;
RA   Prime S.S., Nixon S.V.R., Crane I.J., Stone A., Matthews J.B.,
RA   Maitland N.J., Remnant L., Powell S.K., Game S.M., Scully C.;
RT   "The behaviour of human oral squamous cell carcinoma in cell
RT   culture.";
RL   J. Pathol. 160:259-269(1990).
//
RX   PubMed=1744799; DOI=10.1002/path.1711650208;
RA   Mutlu S., Matthews J.B., Midda M., Scully C., Prime S.S.;
RT   "MHC antigen expression in human oral squamous carcinoma cell lines.";
RL   J. Pathol. 165:129-136(1991).
//
RX   PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8;
RA   Yeudall W.A., Paterson I.C., Patel V., Prime S.S.;
RT   "Presence of human papillomavirus sequences in tumour-derived human
RT   oral keratinocytes expressing mutant p53.";
RL   Eur. J. Cancer B. Oral Oncol. 31:136-143(1995).
//