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Cellosaurus L-82 (CVCL_2098)

[Text version]
Cell line name L-82
Synonyms L82
Accession CVCL_2098
Resource Identification Initiative To cite this cell line use: L-82 (RRID:CVCL_2098)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~40 hours (DSMZ=ACC-597).
Omics: CNV analysis.
Omics: Deep exome analysis.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 427; ALK + HGNC; 7910; NPM1; Name(s)=NPM1-ALK (PubMed=29899875).
Disease Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193)
ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO10,12
D2S133822,25
D3S135817,18
D5S81812
D7S82010,11
D8S117910,14
D13S3178,12
D16S53910,11
D18S5115,16
D19S43312,14
D21S1131.2,33.2
FGA19,27
Penta D10,11
Penta E12
TH019.3
TPOX8,11
vWA16,17

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Publications

PubMed=11908723; DOI=10.1080/10428190210193
Merz H., Lange K., Gaiser T., Muller A., Kapp U., Bittner C., Harder S., Siebert R., Bentz M., Binder T., Diehl V., Feller A.C.
Characterization of a novel human anaplastic large cell lymphoma cell line tumorigenic in SCID mice.
Leuk. Lymphoma 43:165-172(2002)

PubMed=15356658; DOI=10.1038/sj.leu.2403465
Drexler H.G., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of anaplastic large-cell lymphoma.
Leukemia 18:1569-1571(2004)

PubMed=29899875; DOI=10.18632/oncotarget.25489
Krumbholz M., Woessmann W., Zierk J., Seniuk D., Ceppi P., Zimmermann M., Singh V.K., Metzler M., Damm-Welk C.
Characterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma.
Oncotarget 9:26543-26555(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-597
Cell line databases/resources cancercelllines; CVCL_2098
Cell_Model_Passport; SIDM01392
DepMap; ACH-001111
DSMZCellDive; ACC-597
Biological sample resources BioSample; SAMN03473494
Encyclopedic resources Wikidata; Q54900879
Gene expression databases GEO; GSM1217154
GEO; GSM3021103
Polymorphism and mutation databases Progenetix; CVCL_2098
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number25