ID   L-82
AC   CVCL_2098
SY   L82
DR   BioSample; SAMN03473494
DR   cancercelllines; CVCL_2098
DR   Cell_Model_Passport; SIDM01392
DR   DepMap; ACH-001111
DR   DSMZ; ACC-597
DR   DSMZCellDive; ACC-597
DR   GEO; GSM1217154
DR   GEO; GSM3021103
DR   Progenetix; CVCL_2098
DR   Wikidata; Q54900879
RX   PubMed=11908723;
RX   PubMed=15356658;
RX   PubMed=29899875;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: ~40 hours (DSMZ=ACC-597).
CC   Sequence variation: Gene fusion; HGNC; 427; ALK + HGNC; 7910; NPM1; Name(s)=NPM1-ALK (PubMed=29899875).
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): DSMZ=ACC-597
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 8,12
ST   D16S539: 10,11
ST   D18S51: 15,16
ST   D19S433: 12,14
ST   D21S11: 31.2,33.2
ST   D2S1338: 22,25
ST   D3S1358: 17,18
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 10,14
ST   FGA: 19,27
ST   Penta D: 10,11
ST   Penta E: 12
ST   TH01: 9.3
ST   TPOX: 8,11
ST   vWA: 16,17
DI   NCIt; C37193; Anaplastic large cell lymphoma, ALK-positive
DI   ORDO; Orphanet_300895; ALK-positive anaplastic large cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   24Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 26
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RX   PubMed=11908723; DOI=10.1080/10428190210193;
RA   Merz H., Lange K., Gaiser T., Muller A., Kapp U., Bittner C.,
RA   Harder S., Siebert R., Bentz M., Binder T., Diehl V., Feller A.C.;
RT   "Characterization of a novel human anaplastic large cell lymphoma cell
RT   line tumorigenic in SCID mice.";
RL   Leuk. Lymphoma 43:165-172(2002).
//
RX   PubMed=15356658; DOI=10.1038/sj.leu.2403465;
RA   Drexler H.G., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   anaplastic large-cell lymphoma.";
RL   Leukemia 18:1569-1571(2004).
//
RX   PubMed=29899875; DOI=10.18632/oncotarget.25489;
RA   Krumbholz M., Woessmann W., Zierk J., Seniuk D., Ceppi P.,
RA   Zimmermann M., Singh V.K., Metzler M., Damm-Welk C.;
RT   "Characterization and diagnostic application of genomic NPM-ALK fusion
RT   sequences in anaplastic large-cell lymphoma.";
RL   Oncotarget 9:26543-26555(2018).
//