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Cellosaurus GUMBUS (CVCL_2051)

[Text version]
Cell line name GUMBUS
Synonyms Gumbus
Accession CVCL_2051
Resource Identification Initiative To cite this cell line use: GUMBUS (RRID:CVCL_2051)
Comments Virology: EBV-negative.
Doubling time: ~48 hours (DSMZ=ACC-630).
Omics: Transcriptome analysis by RNAseq.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*02:01,23:01
HLA-BB*07:02,44:03
HLA-CC*04:01,07:02
Class II
HLA-DQDQA1*01:01,02:01
DQB1*02:01,05:03
HLA-DRDRB1*14:01,07:01
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 28Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-630

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,19
D3S135814,15
D5S81810,13
D7S8208,10
D8S117913,16
D13S31712,13
D16S53911
D18S5114,16
D19S43314,15
D21S1130,31.2
FGA19,20
Penta D10,12
Penta E10,14
TH019.3
TPOX11
vWA17

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Publications

PubMed=17562080; DOI=10.1007/s00432-007-0241-x
Bracht K., Kiefer T., Dolken G., Bednarski P.J.
Characterization of three B-cell lymphoma cell lines from chemotherapy resistant patients with respect to in vitro sensitivity to 21 antitumor agents, ABC-transporter expression and cellular redox status.
J. Cancer Res. Clin. Oncol. 133:957-967(2007)

PubMed=22885699; DOI=10.1038/nature11378; PMCID=PMC3609867
Schmitz R., Young R.M., Ceribelli M., Jhavar S., Xiao W.-M., Zhang M.-L., Wright G., Shaffer A.L. 3rd, Hodson D.J., Buras E., Liu X.-L., Powell J.I., Yang Y.-D., Xu W.-H., Zhao H., Kohlhammer H., Rosenwald A., Kluin P.M., Muller-Hermelink H.-K., Ott G., Gascoyne R.D., Connors J.M., Rimsza L.M., Campo E., Jaffe E.S., Delabie J., Smeland E.B., Ogwang M.D., Reynolds S.J., Fisher R.I., Braziel R.M., Tubbs R.R., Cook J.R., Weisenburger D.D., Chan W.-C., Pittaluga S., Wilson W., Waldmann T.A., Rowe M., Mbulaiteye S.M., Rickinson A.B., Staudt L.M.
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics.
Nature 490:116-120(2012)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

Cross-references
Cell line collections (Providers) DSMZ; ACC-630
Cell line databases/resources DSMZCellDive; ACC-630
Biological sample resources BioSample; SAMN03473510
Encyclopedic resources Wikidata; Q54871849
Polymorphism and mutation databases Cosmic; 2814539
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number18