ID   GUMBUS
AC   CVCL_2051
SY   Gumbus
DR   BioSample; SAMN03473510
DR   Cosmic; 2814539
DR   DSMZ; ACC-630
DR   DSMZCellDive; ACC-630
DR   Wikidata; Q54871849
RX   PubMed=17562080;
RX   PubMed=22885699;
RX   PubMed=25960936;
CC   Virology: EBV-negative.
CC   Doubling time: ~48 hours (DSMZ=ACC-630).
CC   HLA typing: A*02:01,23:01; B*07:02,44:03; C*04:01,07:02; DQA1*01:01,02:01; DQB1*02:01,05:03; DRB1*14:01,07:01 (PubMed=25960936).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): DSMZ=ACC-630
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 12,13
ST   D16S539: 11
ST   D18S51: 14,16
ST   D19S433: 14,15
ST   D21S11: 30,31.2
ST   D2S1338: 17,19
ST   D3S1358: 14,15
ST   D5S818: 10,13
ST   D7S820: 8,10
ST   D8S1179: 13,16
ST   FGA: 19,20
ST   Penta D: 10,12
ST   Penta E: 10,14
ST   TH01: 9.3
ST   TPOX: 11
ST   vWA: 17
DI   NCIt; C2912; Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   28Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 18
//
RX   PubMed=17562080; DOI=10.1007/s00432-007-0241-x;
RA   Bracht K., Kiefer T., Dolken G., Bednarski P.J.;
RT   "Characterization of three B-cell lymphoma cell lines from
RT   chemotherapy resistant patients with respect to in vitro sensitivity
RT   to 21 antitumor agents, ABC-transporter expression and cellular redox
RT   status.";
RL   J. Cancer Res. Clin. Oncol. 133:957-967(2007).
//
RX   PubMed=22885699; DOI=10.1038/nature11378; PMCID=PMC3609867;
RA   Schmitz R., Young R.M., Ceribelli M., Jhavar S., Xiao W.-M., Zhang M.-L.,
RA   Wright G., Shaffer A.L. 3rd, Hodson D.J., Buras E., Liu X.-L., Powell J.I.,
RA   Yang Y.-D., Xu W.-H., Zhao H., Kohlhammer H., Rosenwald A., Kluin P.M.,
RA   Muller-Hermelink H.-K., Ott G., Gascoyne R.D., Connors J.M.,
RA   Rimsza L.M., Campo E., Jaffe E.S., Delabie J., Smeland E.B.,
RA   Ogwang M.D., Reynolds S.J., Fisher R.I., Braziel R.M., Tubbs R.R.,
RA   Cook J.R., Weisenburger D.D., Chan W.-C., Pittaluga S., Wilson W.,
RA   Waldmann T.A., Rowe M., Mbulaiteye S.M., Rickinson A.B., Staudt L.M.;
RT   "Burkitt lymphoma pathogenesis and therapeutic targets from structural
RT   and functional genomics.";
RL   Nature 490:116-120(2012).
//
RX   PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981;
RA   Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.;
RT   "A catalog of HLA type, HLA expression, and neo-epitope candidates in
RT   human cancer cell lines.";
RL   OncoImmunology 3:e954893.1-e954893.12(2014).
//