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Cellosaurus FKH-1 (CVCL_2041)

[Text version]
Cell line name FKH-1
Synonyms FKH1
Accession CVCL_2041
Resource Identification Initiative To cite this cell line use: FKH-1 (RRID:CVCL_2041)
Comments Population: Japanese.
Doubling time: ~54 hours (PubMed=9753053); ~60-100 hours (DSMZ=ACC-614).
Karyotypic information: 46,XY,t(6;9)(p23;q34) (PubMed=9753053).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-614; RCB=RCB1428

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133818,22
D3S135816,17
D5S81812,13
D7S82012
D8S117910,15
D13S3178,10
D16S53910,11
D18S5115,17
D19S43314,16
D21S1129,32
FGA19,22
Penta D10,13
Penta E12,16
TH018,9
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=9753053; DOI=10.1046/j.1365-2141.1998.00900.x
Hamaguchi H., Nagata K., Yamamoto K., Fujikawa I., Kobayashi M., Eguchi M.
Establishment of a novel human myeloid leukaemia cell line (FKH-1) with t(6;9)(p23;q34) and the expression of dek-can chimaeric transcript.
Br. J. Haematol. 102:1249-1256(1998)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.
Leuk. Res. 25:275-278(2001)

PubMed=28751768; DOI=10.1038/leu.2017.240; PMCID=PMC5630086
Jawhar M., Naumann N., Knut M., Score J., Ghazzawi M.A.M., Schneider B., Kreuzer K.-A., Hallek M., Drexler H.G., Chacko J., Wallis L., Fabarius A., Metzgeroth G., Hofmann W.-K., Chase A., Tapper W.J., Reiter A., Cross N.C.P.
Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia.
Leukemia 31:2271-2273(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-614
RCB; RCB1428 - Discontinued
Cell line databases/resources CLO; CLO_0050983
DSMZCellDive; ACC-614
Biological sample resources BioSample; SAMN01821625
BioSample; SAMN03473503
Encyclopedic resources Wikidata; Q54834946
Gene expression databases GEO; GSM1446758
Polymorphism and mutation databases Cosmic; 975248
Cosmic; 1465949
Cosmic; 2306205
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number24