ID   FKH-1
AC   CVCL_2041
SY   FKH1
DR   CLO; CLO_0050983
DR   BioSample; SAMN01821625
DR   BioSample; SAMN03473503
DR   Cosmic; 975248
DR   Cosmic; 1465949
DR   Cosmic; 2306205
DR   DSMZ; ACC-614
DR   DSMZCellDive; ACC-614
DR   GEO; GSM1446758
DR   RCB; RCB1428
DR   Wikidata; Q54834946
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=9753053;
RX   PubMed=10739008;
RX   PubMed=11226526;
RX   PubMed=28751768;
CC   Population: Japanese.
CC   Doubling time: ~54 hours (PubMed=9753053); ~60-100 hours (DSMZ=ACC-614).
CC   Karyotypic information: 46,XY,t(6;9)(p23;q34) (PubMed=9753053).
CC   Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:3495; ETV6; Name(s)=ETV6-ABL1; Note=In frame (PubMed=28751768).
CC   Sequence variation: Gene fusion; HGNC; HGNC:2768; DEK + HGNC; HGNC:8064; NUP214; Name(s)=DEK-NUP214, DEK-CAN (PubMed=9753053).
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: RCB; RCB1428; probable.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): DSMZ=ACC-614; RCB=RCB1428
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,10
ST   D16S539: 10,11
ST   D18S51: 15,17
ST   D19S433: 14,16
ST   D21S11: 29,32
ST   D2S1338: 18,22
ST   D3S1358: 16,17
ST   D5S818: 12,13
ST   D7S820: 12
ST   D8S1179: 10,15
ST   FGA: 19,22
ST   Penta D: 10,13
ST   Penta E: 12,16
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 24
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=9753053; DOI=10.1046/j.1365-2141.1998.00900.x;
RA   Hamaguchi H., Nagata K., Yamamoto K., Fujikawa I., Kobayashi M.,
RA   Eguchi M.;
RT   "Establishment of a novel human myeloid leukaemia cell line (FKH-1)
RT   with t(6;9)(p23;q34) and the expression of dek-can chimaeric
RT   transcript.";
RL   Br. J. Haematol. 102:1249-1256(1998).
//
RX   PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4;
RA   Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.;
RT   "Frequent microsatellite instability and BAX mutations in T cell acute
RT   lymphoblastic leukemia cell lines.";
RL   Leuk. Res. 24:255-262(2000).
//
RX   PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1;
RA   Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.;
RT   "Corrigendum to: Frequent microsatellite instability and BAX mutations
RT   in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24
RT   (2000), 255-262.";
RL   Leuk. Res. 25:275-278(2001).
//
RX   PubMed=28751768; DOI=10.1038/leu.2017.240; PMCID=PMC5630086;
RA   Jawhar M., Naumann N., Knut M., Score J., Ghazzawi M.A.M.,
RA   Schneider B., Kreuzer K.-A., Hallek M., Drexler H.G., Chacko J.,
RA   Wallis L., Fabarius A., Metzgeroth G., Hofmann W.-K., Chase A.,
RA   Tapper W.J., Reiter A., Cross N.C.P.;
RT   "Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in
RT   myeloid neoplasms with eosinophilia.";
RL   Leukemia 31:2271-2273(2017).
//