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Cellosaurus LT-1 [Contaminated frog cell line] (CVCL_1R49)

[Text version]
Cell line name LT-1 [Contaminated frog cell line]
Accession CVCL_1R49
Resource Identification Initiative To cite this cell line use: LT-1 [Contaminated frog cell line] (RRID:CVCL_1R49)
Comments Group: Fish cell line.
Group: Reptilian cell line.
Problematic cell line: Misidentified/contaminated. Originally thought to be of Lithobates pipiens (frog) origin but found to be a complex mixture of Pimephales promelas FHM and Terrapene carolina TH-1 (PubMed=304896; PubMed=6451928; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00073.
Species of origin Pimephales promelas (Fathead minnow) (NCBI Taxonomy: 90988)
Terrapene carolina (Eastern box turtle) (Testudo carolina) (NCBI Taxonomy: 158814)
Hierarchy Parent: CVCL_3820 (FHM)
Parent: CVCL_4324 (TH-1 subline B1)
Category Hybrid cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=4367239; DOI=10.1093/jnci/53.2.415
Kucera L.S., Simonson J.
Isolation and characterization of a cell line from the cocultivation of Lucke renal tumor cells and nontransformed feeder cells.
J. Natl. Cancer Inst. 53:415-421(1974)

PubMed=304896; DOI=10.1093/jnci/60.3.493
Freed J.J., Toji L.H., Greene A.E.
On the 'Lucke tumor' origin of cell line LT-1.
J. Natl. Cancer Inst. 60:493-495(1978)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151968
Encyclopedic resources Wikidata; Q54903151
Entry history
Entry creation08-Jul-2015
Last entry update21-Mar-2023
Version number13