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Cellosaurus DEN-HSA (CVCL_1R33)

[Text version]
Cell line name DEN-HSA
Synonyms DEN; HSA-Den
Accession CVCL_1R33
Resource Identification Initiative To cite this cell line use: DEN-HSA (RRID:CVCL_1R33)
Comments Doubling time: 16 hours (PubMed=27257868).
Omics: Deep exome analysis.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Canine hemangiosarcoma (NCIt: C122783)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Golden Retriever.
Hierarchy Children:
CVCL_1R34 (Fitz-HSA)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
STR profile Source(s): PubMed=31175136

Markers:
Dog FHC2010231,235
Dog FHC2054168,172
Dog FHC2079275,279
Dog PEZ1115,123
Dog PEZ12285,288
Dog PEZ20176,180
Dog PEZ3119,121
Dog PEZ5103
Dog PEZ6183
Dog PEZ8228,240

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Publications

PubMed=16256156; DOI=10.1016/j.rvsc.2005.09.005
Thamm D.H., Dickerson E.B., Akhtar N., Lewis R., Auerbach R., Helfand S.C., MacEwen E.G.
Biological and molecular characterization of a canine hemangiosarcoma-derived cell line.
Res. Vet. Sci. 81:76-86(2006)

PubMed=17338158; DOI=10.1111/j.1939-1676.2007.tb02936.x
U'Ren L.W., Biller B.J., Elmslie R.E., Thamm D.H., Dow S.W.
Evaluation of a novel tumor vaccine in dogs with hemangiosarcoma.
J. Vet. Intern. Med. 21:113-120(2007)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=22594682; DOI=10.1111/j.1476-5829.2012.00335.x
Lyles S.E., Milner R.J., Kow K., Salute M.E.
In vitro effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine hemangiosarcoma cell lines.
Vet. Comp. Oncol. 10:223-235(2012)

PubMed=22849686; DOI=10.2460/ajvr.73.8.1252
Urbasic A.S., Hynes S., Somrak A.J., Contakos S., Rahman M.M., Liu J., MacNeill A.L.
Oncolysis of canine tumor cells by myxoma virus lacking the serp2 gene.
Am. J. Vet. Res. 73:1252-1261(2012)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=26842912; DOI=10.1111/vco.12197
Hartley G., Faulhaber E., Caldwell A., Coy J., Kurihara J., Guth A., Regan D.P., Dow S.W.
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Cross-references
Encyclopedic resources Wikidata; Q54830976
Gene expression databases GEO; GSM1974786
Entry history
Entry creation08-Jul-2015
Last entry update29-Jun-2023
Version number12