ID   DEN-HSA
AC   CVCL_1R33
SY   DEN; HSA-Den
DR   GEO; GSM1974786
DR   Wikidata; Q54830976
RX   PubMed=16256156;
RX   PubMed=17338158;
RX   PubMed=21908323;
RX   PubMed=22594682;
RX   PubMed=22849686;
RX   PubMed=26842912;
RX   PubMed=27257868;
RX   PubMed=31175136;
CC   Doubling time: 16 hours (PubMed=27257868).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: Golden Retriever.
ST   Source(s): PubMed=31175136
ST   Dog FHC2010: 231,235
ST   Dog FHC2054: 168,172
ST   Dog FHC2079: 275,279
ST   Dog PEZ1: 115,123
ST   Dog PEZ3: 119,121
ST   Dog PEZ5: 103
ST   Dog PEZ6: 183
ST   Dog PEZ8: 228,240
ST   Dog PEZ12: 285,288
ST   Dog PEZ20: 176,180
DI   NCIt; C122783; Canine hemangiosarcoma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 29-06-23; Version: 12
//
RX   PubMed=16256156; DOI=10.1016/j.rvsc.2005.09.005;
RA   Thamm D.H., Dickerson E.B., Akhtar N., Lewis R., Auerbach R.,
RA   Helfand S.C., MacEwen E.G.;
RT   "Biological and molecular characterization of a canine
RT   hemangiosarcoma-derived cell line.";
RL   Res. Vet. Sci. 81:76-86(2006).
//
RX   PubMed=17338158; DOI=10.1111/j.1939-1676.2007.tb02936.x;
RA   U'Ren L.W., Biller B.J., Elmslie R.E., Thamm D.H., Dow S.W.;
RT   "Evaluation of a novel tumor vaccine in dogs with hemangiosarcoma.";
RL   J. Vet. Intern. Med. 21:113-120(2007).
//
RX   PubMed=21908323; DOI=10.1177/1040638711408064;
RA   O'Donoghue L.E., Rivest J.P., Duval D.L.;
RT   "Polymerase chain reaction-based species verification and
RT   microsatellite analysis for canine cell line validation.";
RL   J. Vet. Diagn. Invest. 23:780-785(2011).
//
RX   PubMed=22594682; DOI=10.1111/j.1476-5829.2012.00335.x;
RA   Lyles S.E., Milner R.J., Kow K., Salute M.E.;
RT   "In vitro effects of the tyrosine kinase inhibitor, masitinib
RT   mesylate, on canine hemangiosarcoma cell lines.";
RL   Vet. Comp. Oncol. 10:223-235(2012).
//
RX   PubMed=22849686; DOI=10.2460/ajvr.73.8.1252;
RA   Urbasic A.S., Hynes S., Somrak A.J., Contakos S., Rahman M.M., Liu J.,
RA   MacNeill A.L.;
RT   "Oncolysis of canine tumor cells by myxoma virus lacking the serp2
RT   gene.";
RL   Am. J. Vet. Res. 73:1252-1261(2012).
//
RX   PubMed=26842912; DOI=10.1111/vco.12197;
RA   Hartley G., Faulhaber E.A., Caldwell A., Coy J., Kurihara J.N.,
RA   Guth A., Regan D.P., Dow S.W.;
RT   "Immune regulation of canine tumour and macrophage PD-L1 expression.";
RL   Vet. Comp. Oncol. 15:534-549(2017).
//
RX   PubMed=27257868; DOI=10.1371/journal.pone.0156689;
RA   Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.;
RT   "Intrinsic radiosensitivity and cellular characterization of 27 canine
RT   cancer cell lines.";
RL   PLoS ONE 11:E0156689-E0156689(2016).
//
RX   PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346;
RA   Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.;
RT   "Identifying candidate druggable targets in canine cancer cell lines
RT   using whole exome sequencing.";
RL   Mol. Cancer Ther. 18:1460-1471(2019).
//