Cellosaurus U373-MAGI-CXCR4 (CVCL_1F86)
| Cell line name | U373-MAGI-CXCR4 |
|---|---|
| Synonyms | U373-MAGI-CXCR4CEM |
| Accession | CVCL_1F86 |
| Resource Identification Initiative | To cite this cell line use: U373-MAGI-CXCR4 (RRID:CVCL_1F86) |
| Comments | Population: Caucasian. Characteristics: Transfected with a construct pEQ447 containing the HIV-1 LTR fused to a lacZ reporter gene that contains a MPKKKRK N-terminal sequence directing it to the nucleus (from a parent cell line). Virology: Can be used to detect primary isolates of HIV-1, HIV-2 and SIV (PubMed=9201229). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2561; CXCR4. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872. |
| Disease | Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_1F84 (U373-MAGI) |
| Sex of cell | Male |
| Age at sampling | 75Y |
| Category | Cancer cell line |
| Publications | PubMed=9201229; DOI=10.1006/viro.1997.8606 |
| Cross-references | |
| Cell line collections (Providers) | BEI_Resources; ARP-3596 |
| Encyclopedic resources | Wikidata; Q54973739 |
| Entry history | |
| Entry creation | 08-Jul-2015 |
| Last entry update | 10-Apr-2025 |
| Version number | 12 |