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Cellosaurus HROC32 T3 M1 (CVCL_1D07)

[Text version]
Cell line name HROC32 T3 M1
Synonyms HROC32X
Accession CVCL_1D07
Resource Identification Initiative To cite this cell line use: HROC32 T3 M1 (RRID:CVCL_1D07)
Comments From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
Population: Caucasian.
Characteristics: Established from a patient-derived xenograft established in female NOD SCID mice.
Doubling time: 33.8 +- 5.4 hours (PubMed=25574089).
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Unspecified (CLS=300819).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (CLS=300819).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_YD55 ! B-LCL-HROC32
CVCL_1D06 ! HROC32
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): CLS=300819

Markers:
AmelogeninX
CSF1PO14
D5S81811,12
D7S8208,11
D13S31711,12
D16S53911,12
D21S1131
TH018,9
TPOX8,11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=25574089; DOI=10.3748/wjg.v21.i1.164; PMCID=PMC4284332
Maletzki C., Gock M., Randow M., Klar E., Huhns M., Prall F., Linnebacher M.
Establishment and characterization of cell lines from chromosomal instable colorectal cancer.
World J. Gastroenterol. 21:164-176(2015)

PubMed=31601052; DOI=10.3390/cancers11101520; PMCID=PMC6826890
Mullins C.S., Micheel B., Matschos S., Leuchter M., Burtin F., Krohn M., Huhns M., Klar E., Prall F., Linnebacher M.
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300819
Cell line databases/resources cancercelllines; CVCL_1D07
Encyclopedic resources Wikidata; Q54895284
Polymorphism and mutation databases Cosmic; 2324291
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number19