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Cellosaurus TE 671 (CVCL_1756)

[Text version]
Cell line name TE 671
Synonyms TE-671; TE671; TE671/RD
Accession CVCL_1756
Resource Identification Initiative To cite this cell line use: TE 671 (RRID:CVCL_1756)
Comments Problematic cell line: Contaminated. Shown to be a RD derivative (PubMed=2650908; PubMed=2739733; PubMed=2911385; PubMed=20143388). Originally thought to originate from a 6 year old female patient with a medulloblastoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00101.
Population: Caucasian.
Doubling time: ~70-80 hours (DSMZ=ACC-263).
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Children:
CVCL_2731 (TE 671 Subline No.2)CVCL_9U63 (TE-FLY-A8)CVCL_9U64 (TE-FLY-GALV)
CVCL_9U65 (TELac2)CVCL_9U67 (TeLFBASAF)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): ATCC=HTB-139; CLS=300355; DSMZ=ACC-263; PubMed=11416159

Markers:
AmelogeninX
CSF1PO10,11
D2S133822,23
D3S135815,17
D5S81810,11
D7S8208,12
D8S117911,15
D13S31713
D16S53910,11
D18S5113
D19S43311,14
D21S1128,29
FGA20,21
Penta D11,13
Penta E12
TH019.3
TPOX9
vWA18

Run an STR similarity search on this cell line
Web pages https://www.atcc.org/en/support/technical-support/faqs/te671-atcc-htb-139
https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=892931; DOI=10.1002/ijc.2910200207
McAllister R.M., Isaacs H., Rongey R.W., Peer M., Au W., Soukup S.W., Gardner M.B.
Establishment of a human medulloblastoma cell line.
Int. J. Cancer 20:206-212(1977)

PubMed=6113887
Schlesinger H.R., Rorke-Adams L.B., Jamieson R., Hummeler K.
Neuronal properties of neuroectodermal tumors in vitro.
Cancer Res. 41:2573-2575(1981)

PubMed=3335022
Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer Res. 48:589-601(1988)

PubMed=2650908; DOI=10.1093/carcin/10.5.899
Stratton M.R., Darling J.L., Pilkington G.J., Lantos P.L., Reeves B.R., Cooper C.S.
Characterization of the human cell line TE671.
Carcinogenesis 10:899-905(1989)

PubMed=2911385; DOI=10.1038/337311c0
Stratton M.R., Reeves B.R., Cooper C.S.
Misidentified cell.
Nature 337:311-312(1989)

PubMed=2739733; DOI=10.1038/340106b0
Chen T.-R., Dorotinsky C.S., Macy M.L., Hay R.J.
Cell identity resolved.
Nature 340:106-106(1989)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=11668190; DOI=10.1177/002215540104901105
Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=24335698; DOI=10.1093/neuonc/not202; PMCID=PMC3895385
An Q., Fillmore H.L., Vouri M., Pilkington G.J.
Brain tumor cell line authentication, an efficient alternative to capillary electrophoresis by using a microfluidics-based system.
Neuro-oncol. 16:265-273(2014)

Cross-references
Cell line collections (Providers) ATCC; HTB-139 - Discontinued
CLS; 300355
DSMZ; ACC-263 - Discontinued
ECACC; 89071904 - Discontinued
IZSLER; BS TCL 64
NCBI_Iran; C436
Cell line databases/resources CLO; CLO_0009305
CLO; CLO_0009317
CLDB; cl4495
CLDB; cl4496
CLDB; cl4497
cancercelllines; CVCL_1756
DSMZCellDive; ACC-263
Anatomy/cell type resources BTO; BTO_0002605
Biological sample resources BioSample; SAMN03151901
Chemistry resources ChEMBL-Cells; CHEMBL3307468
ChEMBL-Targets; CHEMBL615012
PubChem_Cell_line; CVCL_1756
Encyclopedic resources Wikidata; Q54971989
Polymorphism and mutation databases Cosmic; 970091
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number33